Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 12/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8290204 | 0.93 | CMA1 (0.66) | CMA1 | |
| SCHEMBL14001199 | 0.90 | CMA1 (0.57) | CMA1 | |
| SCHEMBL13172303 | 0.86 | CMA1 (0.65) | CMA1KDR | |
| SCHEMBL13489673 | 0.83 | CMA1 (0.68) | CMA1 | |
| SCHEMBL10330708 | 0.80 | CMA1 (0.83) | CMA1 | |
| SCHEMBL409980 | 0.80 | CMA1 (0.75) | CMA1 | |
| SCHEMBL409979 | 0.80 | CMA1 (0.75) | CMA1 | |
| SCHEMBL3141528 | 0.78 | CMA1 (0.78) | CMA1 | |
| SCHEMBL3141532 | 0.78 | CMA1 (0.78) | CMA1 | |
| SCHEMBL3238437 | 0.78 | CMA1 (0.72) | CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048513-A1 | Novel inhibitors of chymase | HAWKINS MICHAEL J | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048513-A1 | Novel inhibitors of chymase | CMA1, SERPINB1, TPSAB1 | CMA1 1/4885KDR 4589/4885FLT1 3128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.