Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HRAS | P01112 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | TOP1 | P11387 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14027353 | 0.90 | P2RY12 (0.40) | P2RY12KMT2APKMMEN1NPC1 | |
| SCHEMBL14003295 | 0.90 | P2RY12 (0.40) | P2RY12KMT2APKMMEN1NPC1 | |
| SCHEMBL14003296 | 0.85 | KMT2A (0.39) | P2RY12KMT2APKMMEN1NPC1 | |
| SCHEMBL14003294 | 0.82 | P2RY12 (0.40) | P2RY12KMT2AMEN1NPSR1MAPT | |
| SCHEMBL5333313 | 0.80 | P2RY12 (0.37) | P2RY12KMT2APKMMEN1NPC1 | |
| SCHEMBL12307516 | 0.78 | AR (0.36) | KMT2APKMMEN1NPC1HPGD | |
| SCHEMBL12934361 | 0.78 | AR (0.36) | KMT2APKMMEN1NPC1HPGD | |
| SCHEMBL2071768 | 0.73 | HDAC1 (0.58) | MAPTHDAC1HDAC2HDAC8HRAS | |
| SCHEMBL14181021 | 0.70 | P2RY12 (0.44) | P2RY12KMT2APKMMEN1NPC1 | |
| SCHEMBL14181033 | 0.70 | P2RY12 (0.44) | P2RY12KMT2APKMMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456294-B2 | Hairpin polyamide | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-11-25 | — | — | US | disclosed |
| US-7456294-B2 | Hairpin polyamide | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-11-25 | — | — | US | disclosed |