SCHEMBL5333313

SCHEMBL5333313

COC(=O)c1cc(NC(=O)c2nc([N+](=O)[O-])cn2C)cn1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY12 Q9H244 1/20 0.37
KMT2A Q03164 6/20 0.35
MEN1 O00255 5/20 0.35
AR P10275 1/20 0.35
LMNA P02545 3/20 0.35
MITF O75030 2/20 0.35
S1PR4 O95977 1/20 0.35
S1PR1 P21453 1/20 0.35
NTSR1 P30989 1/20 0.35
HTT P42858 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
P2RX3 P56373 2/20 0.34
MAPT P10636 2/20 0.33
ALDH1A1 P00352 2/20 0.33
POLB P06746 1/20 0.33
THRB P10828 1/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14003294 0.98 P2RY12 (0.40) P2RY12KMT2AMEN1ARLMNA
SCHEMBL12307516 0.88 AR (0.36) KMT2AMEN1ARLMNAMITF
SCHEMBL12934361 0.88 AR (0.36) KMT2AMEN1ARLMNAMITF
SCHEMBL15385157 0.82 HDAC1 (0.42) P2RY12KMT2AMEN1ARLMNA
SCHEMBL26004721 0.82 HDAC1 (0.42) P2RY12KMT2AMEN1ARLMNA
SCHEMBL14543164 0.82 P2RY12 (0.42) P2RY12KMT2AMEN1HDAC1HDAC2
SCHEMBL20833590 0.81 P2RY12 (0.39) P2RY12HDAC1HDAC2HDAC8P2RX3
SCHEMBL6430445 0.81 P2RY12 (0.39) P2RY12HDAC1HDAC2HDAC8P2RX3
SCHEMBL14003293 0.80 P2RY12 (0.40) P2RY12KMT2AMEN1ARLMNA
SCHEMBL5335785 0.80 P2RY12 (0.43) P2RY12LMNAHDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023149487-A1 METHOD FOR PRODUCING PYRROLE-IMIDAZOLE POLYAMIDE 国立大学法人千葉大学 2023-08-10 WO disclosed
WO-2007045096-A1 OLIGOHETEROAROMATIC LUMINISCENT ASSEMBLIES AS HIGH-AFFINITY DNA SEQUENCE-DIRECTED LIGANDS UNIVERSITY OF SASKATCHEWAN (CA) 2007-04-26 WO disclosed