Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.57 |
| ▸ | PPARG | P37231 | 11/20 | 0.57 |
| ▸ | PPARD | Q03181 | 5/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1400536 | 0.86 | PPARD (0.70) | PPARAPPARD | |
| SCHEMBL1400265 | 0.85 | PPARA (0.58) | PPARAPPARG | |
| SCHEMBL12798920 | 0.83 | PPARD (0.61) | PPARAPPARD | |
| SCHEMBL3124670 | 0.83 | PPARA (0.65) | PPARAPPARGPPARD | |
| SCHEMBL1400760 | 0.83 | PPARA (0.76) | PPARAPPARGPPARD | |
| SCHEMBL1400701 | 0.79 | PPARA (0.57) | PPARAPPARG | |
| SCHEMBL1400992 | 0.78 | PPARG (0.70) | PPARAPPARG | |
| SCHEMBL1400751 | 0.77 | PPARA (0.35) | PPARAPPARGPPARD | |
| SCHEMBL1400465 | 0.77 | PPARA (0.58) | PPARAPPARGPPARD | |
| SCHEMBL1400883 | 0.76 | PPARA (0.55) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578715-B1 | INDANE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS, INTERMEDIATES, AND METHOD OF PREPARATION | BAYER PHARMACEUTICALS CORP (US) | 2011-03-02 | — | — | EP | disclosed |