Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.35 |
| ▸ | PPARD | Q03181 | 6/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1400385 | 0.77 | PPARA (0.57) | PPARAPPARDPPARG | |
| SCHEMBL3124670 | 0.66 | PPARA (0.65) | PPARAPPARDPPARG | |
| SCHEMBL1400265 | 0.62 | PPARA (0.58) | PPARAPPARG | |
| SCHEMBL1400711 | 0.55 | RAB9A (0.42) | — | |
| SCHEMBL23978901 | 0.54 | CRHR1 (0.40) | — | |
| SCHEMBL22808490 | 0.53 | OPRM1 (0.33) | — | |
| SCHEMBL8301036 | 0.53 | MTNR1B (0.38) | PPARA | |
| SCHEMBL22456647 | 0.53 | BIRC2 (0.35) | — | |
| SCHEMBL1400410 | 0.53 | ALDH1A1 (0.43) | — | |
| SCHEMBL8298174 | 0.52 | GRM7 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578715-B1 | INDANE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS, INTERMEDIATES, AND METHOD OF PREPARATION | BAYER PHARMACEUTICALS CORP (US) | 2011-03-02 | — | — | EP | disclosed |