Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | EPHX1 | P07099 | 14/20 | 0.61 |
| ▸ | FPR3 | P25089 | 2/20 | 0.55 |
| ▸ | FPR2 | P25090 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | RAD52 | P43351 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25477818 | 0.88 | RAD52 (0.55) | KDM4EEPHX1RAD52 | |
| SCHEMBL24001250 | 0.86 | KDM4E (0.59) | KDM4EFPR3FPR2ALDH1A1EPHX2 | |
| SCHEMBL25477820 | 0.86 | RAD52 (0.53) | KDM4EEPHX1RAD52 | |
| SCHEMBL30958387 | 0.85 | EPHX1 (0.68) | KDM4EEPHX1ALDH1A1EPHX2 | |
| SCHEMBL25477811 | 0.84 | KDM4E (0.59) | KDM4EALDH1A1RAD52 | |
| SCHEMBL3064749 | 0.84 | KDM4E (0.54) | KDM4EEPHX1FPR3FPR2ALDH1A1 | |
| SCHEMBL21827446 | 0.84 | KDM4E (0.60) | KDM4EFPR3FPR2ALDH1A1RAD52 | |
| SCHEMBL3896010 | 0.84 | EPHX1 (0.54) | KDM4EEPHX1ALDH1A1RAD52 | |
| Cyclohexane SCHEMBL5496549 | 0.84 | EPHX1 (0.86) | EPHX1EPHX2 | |
| SCHEMBL25480324 | 0.84 | KDM4E (0.49) | KDM4EEPHX1ALDH1A1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456220-B2 | Immunodulatory compositions and methods of use thereof | GENZYME CORPORATION (US) | 2008-11-25 | — | — | US | disclosed |