Sugi Predict

Sugi Predict / Compounds / SCHEMBL14005778

SCHEMBL14005778

SCHEMBL14005778

Cc1ccc(-n2cc3ccccc3n2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADORA3 P0DMS8 13/20 0.54
▸ ADORA1 P30542 5/20 0.54
▸ ADORA2A P29274 3/20 0.54
▸ MEN1 O00255 3/20 0.54
▸ NPC1 O15118 3/20 0.54
▸ RAB9A P51151 3/20 0.54
▸ KMT2A Q03164 3/20 0.54
▸ LMNA P02545 2/20 0.54
▸ MAPT P10636 2/20 0.54
▸ SMN1; SMN2 Q16637 2/20 0.54
▸ NFKB1 P19838 1/20 0.54
▸ CASP3 P42574 1/20 0.54
▸ NFKB2 Q00653 1/20 0.54
▸ RELA Q04206 1/20 0.54
▸ SENP8 Q96LD8 1/20 0.54
▸ SENP7 Q9BQF6 1/20 0.54
▸ SENP6 Q9GZR1 1/20 0.54
▸ ESR2 Q92731 1/20 0.47
▸ ADORA2B P29275 1/20 0.44
▸ CA12 O43570 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7848179 0.90 ESR2 (0.55) ADORA3ADORA1ADORA2AMEN1NPC1
SCHEMBL2979520 0.84 ESR2 (0.62) ADORA3ADORA1ADORA2AMEN1NPC1
SCHEMBL28748648 0.84 ESR2 (0.46) ADORA3ADORA1ADORA2AMEN1NPC1
SCHEMBL1712561 0.81 ADORA3 (0.54) ADORA3ADORA2AMEN1NPC1RAB9A
SCHEMBL2264916 0.81 ESR2 (0.47) ADORA3ADORA1ADORA2AMEN1NPC1
SCHEMBL14036890 0.81 ESR2 (0.47) ADORA3ADORA1ADORA2AMEN1NPC1
SCHEMBL3853197 0.81 ESR2 (0.47) ADORA3ADORA1ADORA2AMEN1NPC1
SCHEMBL1872721 0.81 ESR2 (0.65) ADORA3ADORA1ADORA2AMEN1NPC1
SCHEMBL19763359 0.81 NPC1 (0.66) ADORA3ADORA1ADORA2AMEN1NPC1
SCHEMBL28540825 0.81 ESR2 (0.47) ADORA3ADORA1ADORA2AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184598-A Photocatalytic preparation method and application of N- (2-phenyl-2H-indazole-3-yl) benzamide compound 河南师范大学 2024-06-14 — — CN disclosed
CN-115385858-B Photocatalytic preparation method of 2-phenyl-2H-indazole-3-carboxamide compound 河南师范大学 2024-03-01 — — CN disclosed
CN-113698349-B Aqueous phase photocatalysis preparation method of 2- (2-phenyl-2H-indazole-3-yl) acetate compound 河南师范大学 2023-08-01 — — CN disclosed
CN-116332851-A Cyanomethyl phenyl indazole compound and preparation method thereof 河南中医药大学 2023-06-27 — — CN disclosed
CN-115613060-A Method for synthesizing C-3 phosphorylated 2H-indazole compound by direct electrochemical oxidation 浙江工业大学 2023-01-17 — — CN disclosed
CN-115385858-A Photocatalytic preparation method of 2-phenyl-2H-indazole-3-formamide compound 河南师范大学 2022-11-25 — — CN disclosed
CN-114989089-A Photocatalytic preparation method of 3-alkyl-2-phenyl indazole compound 河南师范大学 2022-09-02 — — CN disclosed
CN-113862705-A Electrochemical synthesis method of 2-aryl-3-halo-2H-indazole compound 浙江工业大学 2021-12-31 — — CN disclosed
CN-113698349-A Water-phase photocatalytic preparation method of 2- (2-phenyl-2H-indazole-3-yl) acetate compounds 河南师范大学 2021-11-26 — — CN disclosed
CN-107602472-B Preparation method of 2-substituted-2H-indazole compound 上海应用技术大学 2020-10-09 — — CN disclosed
CN-107602472-A A kind of preparation method of 2 substitution 2H indazole compounds 上海应用技术大学 2018-01-19 — — CN disclosed
US-20080274423-A1 OPTICAL INFORMATION RECORDING MEDIUM AND METHOD OF RECORDING INFORMATION FUJIFILM CORPORATION (JP) 2008-11-06 — — US disclosed
US-20080274423-A1 OPTICAL INFORMATION RECORDING MEDIUM AND METHOD OF RECORDING INFORMATION FUJIFILM CORPORATION (JP) 2008-11-06 — — US disclosed