Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 14/20 | 0.69 |
| ▸ | DRD3 | P35462 | 12/20 | 0.69 |
| ▸ | HTR1A | P08908 | 4/20 | 0.69 |
| ▸ | HTR2A | P28223 | 3/20 | 0.69 |
| ▸ | HTR2C | P28335 | 3/20 | 0.69 |
| ▸ | DRD4 | P21917 | 8/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | HTR2B | P41595 | 2/20 | 0.62 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1460505 | 0.92 | DRD2 (0.83) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL14006049 | 0.85 | DRD2 (0.66) | DRD2DRD3DRD4KCNH2CYP1A2 | |
| SCHEMBL1543274 | 0.85 | DRD2 (0.65) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL14006131 | 0.83 | DRD2 (0.65) | DRD2DRD3HTR1ADRD4KCNH2 | |
| SCHEMBL14006130 | 0.83 | DRD2 (0.63) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL7058606 | 0.82 | DRD2 (0.83) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL3120754 | 0.82 | DRD2 (0.67) | DRD2DRD3HTR1ADRD4ADRA1D | |
| SCHEMBL3086024 | 0.81 | DRD2 (1.00) | DRD2DRD3HTR1AHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL6709052 | 0.81 | DRD2 (0.66) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL3117641 | 0.81 | DRD2 (0.63) | DRD2DRD3HTR1ADRD4ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080275028-A1 | Modulators or Alpha7 Nicotinic Acetylcholine Receptors and Therapeutic Uses Thereof | SIENA BIOTECH S.P.A. (IT) | 2008-11-06 | — | — | US | disclosed |
| US-20080275028-A1 | Modulators or Alpha7 Nicotinic Acetylcholine Receptors and Therapeutic Uses Thereof | SIENA BIOTECH S.P.A. (IT) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275028-A1 | Modulators or Alpha7 Nicotinic Acetylcholine Receptors and Therapeutic Uses Thereof | CHRNA7, CHRNA5, CHRNA1 | DRD2 582/4885DRD3 597/4885HTR1A 108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.