Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 4/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL440570 | 0.92 | — | — | |
| SCHEMBL12232836 | 0.89 | MAPT (0.45) | MAPTKDM5AKDM4CSIGMAR1S1PR2 | |
| Hydrochloric Acid SCHEMBL27829624 | 0.89 | — | — | |
| SCHEMBL7849316 | 0.89 | MAPT (0.50) | MAPTSIGMAR1S1PR2S1PR1S1PR3 | |
| SCHEMBL1404135 | 0.86 | — | — | |
| SCHEMBL441881 | 0.86 | — | — | |
| SCHEMBL23945948 | 0.86 | SIGMAR1 (0.46) | MAPTKDM5AKDM4CSIGMAR1S1PR2 | |
| SCHEMBL735154 | 0.84 | S1PR2 (0.52) | KDM5AKDM4CS1PR2S1PR1S1PR3 | |
| Dimethylamine SCHEMBL14975983 | 0.84 | MAPT (0.41) | MAPTKDM5AKDM4CSIGMAR1S1PR2 | |
| SCHEMBL15790830 | 0.84 | MAPT (0.41) | MAPTKDM5AKDM4CS1PR2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944836-B2 | Amine composition | EVONIK DEGUSSA GMBH (DE) | 2018-04-17 | — | — | US | disclosed |
| US-20150368531-A1 | Amine Composition | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2015-12-24 | — | — | US | disclosed |
| US-9133306-B2 | Amine composition | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2015-09-15 | — | — | US | disclosed |
| US-20080275191-A1 | polyamines used as curing agents and as polymerization catalysts or chain extenders in urethane applications | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2008-11-06 | — | — | US | disclosed |