Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 3/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12571328 | 0.88 | ABCB1 (0.54) | ABCB1PDK1PDK2PDK3PDK4 | |
| SCHEMBL13243337 | 0.81 | HTT (0.44) | MAPTKLK7KLK5SYKL3MBTL1 | |
| SCHEMBL26374272 | 0.80 | SMN1; SMN2 (0.50) | MAPTKLK7KLK5SYKL3MBTL1 | |
| SCHEMBL13430793 | 0.78 | SIRT2 (0.52) | MAPTKLK7KLK5SYKITGB3 | |
| SCHEMBL9178484 | 0.77 | MAPT (0.48) | MAPTKLK7KLK5SYKL3MBTL1 | |
| SCHEMBL9179022 | 0.77 | MAPT (0.48) | MAPTKLK7KLK5SYKL3MBTL1 | |
| SCHEMBL13430794 | 0.77 | SIRT2 (0.52) | MAPTKLK7KLK5SYKITGB3 | |
| SCHEMBL28633511 | 0.76 | MAPT (0.52) | MAPTKLK7KLK5SYKL3MBTL1 | |
| SCHEMBL13430791 | 0.76 | SYK (0.48) | MAPTKLK7KLK5SYKL3MBTL1 | |
| SCHEMBL20556340 | 0.76 | SYK (0.51) | MAPTKLK7KLK5SYKITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456184-B2 | Melanocortin receptor-specific compounds | PALATIN TECHNOLOGIES INC. (US) | 2008-11-25 | — | — | US | disclosed |