Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 8/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14008968 | 0.88 | RAB9A (0.41) | S1PR4PKMALDH1A1MAPTLMNA | |
| SCHEMBL14009011 | 0.76 | NPC1 (0.39) | ALDH1A1LMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14008940 | 0.74 | APOBEC3A (0.49) | S1PR4PKMMAPTRAB9ANPC1 | |
| SCHEMBL14009031 | 0.69 | S1PR4 (0.51) | S1PR4PKMALDH1A1MAPTLMNA | |
| SCHEMBL11206018 | 0.63 | NPC1 (0.55) | MAPTLMNAHPGDRAB9ANPC1 | |
| SCHEMBL23657657 | 0.63 | NPC1 (0.67) | PKMALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL11826733 | 0.63 | RAB9A (0.65) | ALDH1A1MAPTLMNAHPGDRAB9A | |
| SCHEMBL14009239 | 0.62 | RAB9A (0.56) | ALDH1A1MAPTLMNAHPGDRAB9A | |
| SCHEMBL11996735 | 0.62 | HDAC1 (0.39) | ALDH1A1MAPTHPGDRAB9ANPC1 | |
| SCHEMBL14009173 | 0.62 | KLKB1 (0.57) | S1PR4PKMMAPTLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8808952-B2 | Composition for forming charge transporting film, electrophotographic photoreceptor, process cartridge, and image forming apparatus | FUJI XEROX CO., LTD. (JP) | 2014-08-19 | — | — | US | disclosed |
| US-7446195-B2 | High affinity thiophene-based and furan-based kinase ligands | SCHERING CORPORATION (US) | 2008-11-04 | — | — | US | disclosed |
| US-7446195-B2 | High affinity thiophene-based and furan-based kinase ligands | SCHERING CORPORATION (US) | 2008-11-04 | — | — | US | disclosed |
| US-20070043045-A1 | Novel high affinity thiophene-based and furan-based kinase ligands | SCHERING CORPORATION | 2007-02-22 | — | — | US | disclosed |
| US-20070043045-A1 | Novel high affinity thiophene-based and furan-based kinase ligands | SCHERING CORPORATION | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043045-A1 | Novel high affinity thiophene-based and furan-based kinase ligands | CDKL2, CDK2, CDKL1 | S1PR4 2719/4885PKM 879/4885ALDH1A1 4225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.