Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | GRM7 | Q14831 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14008933 | 0.87 | MAPT (0.45) | MAPTPOLBNPC1RAB9AKDM4E | |
| SCHEMBL14008963 | 0.86 | CYP1A2 (0.47) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL14008940 | 0.76 | APOBEC3A (0.49) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL14009011 | 0.76 | NPC1 (0.39) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL14009325 | 0.76 | KMT2A (0.52) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL14009082 | 0.75 | MAPT (0.53) | CYP1A2CYP3A4MAPTPOLBKMT2A | |
| SCHEMBL14009103 | 0.73 | KMT2A (0.44) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL14009249 | 0.73 | RAB9A (0.49) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL14009077 | 0.73 | MEN1 (0.55) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL14009015 | 0.73 | MAPT (0.46) | MAPTGRM7HSP90AA1ATMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8808952-B2 | Composition for forming charge transporting film, electrophotographic photoreceptor, process cartridge, and image forming apparatus | FUJI XEROX CO., LTD. (JP) | 2014-08-19 | — | — | US | disclosed |
| US-7446195-B2 | High affinity thiophene-based and furan-based kinase ligands | SCHERING CORPORATION (US) | 2008-11-04 | — | — | US | disclosed |
| US-7446195-B2 | High affinity thiophene-based and furan-based kinase ligands | SCHERING CORPORATION (US) | 2008-11-04 | — | — | US | disclosed |
| US-20070043045-A1 | Novel high affinity thiophene-based and furan-based kinase ligands | SCHERING CORPORATION | 2007-02-22 | — | — | US | disclosed |
| US-20070043045-A1 | Novel high affinity thiophene-based and furan-based kinase ligands | SCHERING CORPORATION | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043045-A1 | Novel high affinity thiophene-based and furan-based kinase ligands | CDKL2, CDK2, CDKL1 | CYP1A2 2310/4885CYP3A4 3394/4885CYP2C9 3263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.