⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956487 | 0.95 | NPC1 (0.43) | — | |
| SCHEMBL386138 | 0.93 | NPC1 (0.47) | — | |
| SCHEMBL29951010 | 0.93 | NPC1 (0.47) | — | |
| SCHEMBL10749421 | 0.90 | — | — | |
| SCHEMBL29957753 | 0.82 | MCHR1 (0.31) | — | |
| SCHEMBL23270238 | 0.82 | NPC1 (0.41) | — | |
| SCHEMBL8697181 | 0.80 | SPHK1 (0.35) | — | |
| SCHEMBL19172102 | 0.80 | — | — | |
| SCHEMBL23270243 | 0.80 | NPC1 (0.39) | — | |
| SCHEMBL27599955 | 0.80 | NPC1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230103337-A1 | MEDICINE FOR IMPROVING STATE OF PREGNANCY, AND USE THEREOF | Yamaguchi, Koushi (JP) | 2023-04-06 | — | — | US | disclosed |
| US-11541040-B2 | Medicine for improving state of pregnancy, and use thereof | Yamaguchi, Kouchi (JP) | 2023-01-03 | — | — | US | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-3977995-A1 | TACROLIMUS FOR AMELIORATING PREGNANCY CONDITIONS | Yamaguchi, Koushi (JP) | 2022-04-06 | — | — | EP | disclosed |
| EP-3900729-A1 | AGENT FOR IMPROVING INFERTILITY, RECURRENT MISCARRIAGE, AND STATE OF PREGNANCY | Yamaguchi, Koushi (JP) | 2021-10-27 | — | — | EP | disclosed |
| EP-3246036-B1 | MEDICINE FOR IMPROVING PREGNANCY-INDUCED HYPERTENSION SYNDROME | YAMAGUCHI KOUSHI (JP) | 2021-10-13 | — | — | EP | disclosed |
| CN-113226331-A | Medicine for improving infertility or pregnancy state | 山口晃史 | 2021-08-06 | — | — | CN | disclosed |
| US-20210228551-A1 | THERAPEUTIC AGENT FOR HUMORAL IMMUNITY-RELATED DISEASES IN MATERNOFETAL RELATIONSHIP | YAMAGUCHI KOUSHI (JP) | 2021-07-29 | — | — | US | disclosed |
| EP-3834826-A1 | THERAPEUTIC AGENT FOR HUMORAL IMMUNITY-RELATED DISEASES IN MATERNO-FETAL RELATIONSHIP | Yamaguchi, Koushi (JP) | 2021-06-16 | — | — | EP | disclosed |
| CN-112533599-A | Therapeutic agent for humoral immunity-related diseases in maternal-fetal relationship | 山口晃史 | 2021-03-19 | — | — | CN | disclosed |
| EP-0444659-A2 | A pharmaceutical solution comprising derivatives of FK506 | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-04 | — | — | EP | disclosed |
| EP-0428169-A2 | Aqueous liquid formulations | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-22 | — | — | EP | disclosed |
| EP-0428365-A1 | Aminomacrolides and derivatives having immunosuppressive activity | MERCK & CO. INC. (US) | 1991-05-22 | — | — | EP | disclosed |
| EP-0423714-A2 | Hair revitalizing agent | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-04-24 | — | — | EP | disclosed |
| EP-0406791-A2 | Aqueous liquid composition for external use | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-01-09 | — | — | EP | disclosed |
| EP-0399579-A1 | Macrolides having immunosuppressive activity | MERCK & CO. INC. (US) | 1990-11-28 | — | — | EP | disclosed |
| US-4956352-A | TREATING AUTOIMMUNE DISEASES, RESISTANCE TO TRANSPLANTATION, INFECTIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| US-4929611-A | ANTIBODY INHIBITORS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-05-29 | — | — | US | disclosed |
| US-4894366-A | Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-01-16 | — | — | US | disclosed |
| EP-0184162-A2 | Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-06-11 | — | — | EP | disclosed |