SCHEMBL8697181

SCHEMBL8697181

O=CCCOC1CCOCC1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 1/20 0.35
PRMT5 O14744 1/20 0.32
WDR77 Q9BQA1 1/20 0.32
KAT2B Q92831 1/20 0.32
BAZ2B Q9UIF8 1/20 0.32
DCPS Q96C86 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29952542 0.88 ATF4 (0.31)
SCHEMBL10749421 0.84
SCHEMBL29956487 0.80 NPC1 (0.43)
SCHEMBL1400901 0.80
SCHEMBL386138 0.78 NPC1 (0.47)
SCHEMBL29951010 0.78 NPC1 (0.47)
SCHEMBL1318740 0.78 SPHK1 (0.34) SPHK1
SCHEMBL578881 0.76 SPHK1 (0.37) SPHK1
SCHEMBL19172102 0.75
SCHEMBL3108732 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-5807891-A RETROVIRUSES NOVARTIS AG (CH) 1998-09-15 US disclosed