Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 10/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14345108 | 0.91 | PRKCA (0.49) | PRKCAMMP12NR1I2KCNH2CYP3A4 | |
| SCHEMBL14009766 | 0.91 | PRKCA (0.49) | PRKCAMMP12NR1I2KCNH2CYP3A4 | |
| SCHEMBL13841676 | 0.85 | NR1I2 (0.49) | PRKCAMMP12NR1I2KCNH2CYP3A4 | |
| SCHEMBL14110712 | 0.84 | NR1I2 (0.49) | PRKCAMMP12NR1I2KCNH2CYP3A4 | |
| SCHEMBL13841704 | 0.84 | KCNH2 (0.51) | PRKCAMMP12NR1I2KCNH2CYP3A4 | |
| SCHEMBL14009588 | 0.83 | KCNH2 (0.47) | PRKCAMMP12NR1I2KCNH2CYP3A4 | |
| SCHEMBL13356098 | 0.80 | NR1I2 (0.62) | PRKCAMMP12NR1I2KCNH2CYP3A4 | |
| SCHEMBL1734222 | 0.80 | NR1I2 (0.65) | PRKCAMMP12NR1I2KCNH2CYP3A4 | |
| SCHEMBL13356029 | 0.79 | KCNH2 (0.58) | PRKCAMMP12NR1I2KCNH2CYP3A4 | |
| SCHEMBL4487739 | 0.79 | NR1I2 (0.48) | PRKCAMMP12NR1I2KCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456167-B2 | Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-11-25 | — | — | US | disclosed |
| US-20070275947-A1 | Cyclopropyl Fused Indolobenzazepine HCV NS5B Inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275947-A1 | Cyclopropyl Fused Indolobenzazepine HCV NS5B Inhibitors | HAVCR2, ZC3HAV1, HCCS | PRKCA 3901/4885MMP12 4103/4885NR1I2 298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.