SCHEMBL14010049

SCHEMBL14010049

Cc1cccc(Oc2cccc(N3C(=O)c4ccc(Oc5ccc6c(c5)C(=O)N(C)C6=O)cc4C3=O)c2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.56
MEN1 O00255 7/20 0.52
KMT2A Q03164 7/20 0.52
ALDH1A1 P00352 5/20 0.51
MAPK1 P28482 2/20 0.51
POLB P06746 1/20 0.51
MAPT P10636 1/20 0.51
LPAR1 Q92633 1/20 0.47
LPAR5 Q9H1C0 1/20 0.47
LPAR3 Q9UBY5 1/20 0.47
GAA P10253 1/20 0.47
HPGD P15428 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HSD17B10 Q99714 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
USP2 O75604 1/20 0.45
KEAP1 Q14145 1/20 0.45
NFE2L2 Q16236 1/20 0.45
LYN P07948 1/20 0.45
HTT P42858 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12574001 0.99 BRD4 (0.59) BRD4MEN1KMT2AALDH1A1MAPK1
SCHEMBL14010053 0.93 BRD4 (0.58) BRD4MEN1KMT2AALDH1A1MAPK1
SCHEMBL14010063 0.92 BRD4 (0.48) BRD4MEN1KMT2AALDH1A1MAPK1
SCHEMBL26030942 0.91 MEN1 (0.51) BRD4MEN1KMT2AALDH1A1MAPK1
SCHEMBL11892525 0.91 BRD4 (0.50) BRD4MEN1KMT2AALDH1A1MAPK1
SCHEMBL29311934 0.91 BRD4 (0.51) BRD4MEN1KMT2AALDH1A1MAPK1
SCHEMBL25627495 0.90 BRD4 (0.50) BRD4MEN1KMT2AALDH1A1MAPK1
SCHEMBL12201312 0.89 BRD4 (0.48) BRD4MEN1KMT2AALDH1A1MAPK1
SCHEMBL14729123 0.88 MEN1 (0.57) BRD4MEN1KMT2AALDH1A1MAPK1
SCHEMBL25627492 0.88 HSD17B10 (0.52) BRD4MEN1KMT2AALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8969128-B2 Method of fabricating thin film transistor substrate and organic light emitting display device using the same LG DISPLAY CO., LTD. (KR) 2015-03-03 US disclosed
US-20130240888-A1 METHOD OF FABRICATING THIN FILM TRANSISTOR SUBSTRATE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE USING THE SAME LG DISPLAY CO., LTD. 2013-09-19 US disclosed
US-7445852-B2 Magnetic substrate, laminate of magnetic substrate and method for producing thereof MITSUI CHEMICALS, INC. (JP) 2008-11-04 US disclosed