SCHEMBL14010052

SCHEMBL14010052

Cc1ccc(Oc2cccc(N3C(=O)c4ccc(-c5ccc6c(c5)C(=O)N(C)C6=O)cc4C3=O)c2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.51
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
MAPK1 P28482 2/20 0.49
POLB P06746 1/20 0.49
LPAR1 Q92633 2/20 0.48
LPAR3 Q9UBY5 2/20 0.48
LPAR5 Q9H1C0 1/20 0.48
ALDH1A1 P00352 4/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 2/20 0.46
HSD17B10 Q99714 2/20 0.44
MCHR1 Q99705 1/20 0.43
ESR1 P03372 1/20 0.42
APP P05067 1/20 0.42
NPC1 O15118 1/20 0.42
TSHR P16473 1/20 0.42
CASP1 P29466 1/20 0.42
RAB9A P51151 1/20 0.42
CASP7 P55210 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12317361 0.94 BRD4 (0.60) BRD4MEN1KMT2AMAPK1POLB
SCHEMBL14010053 0.94 BRD4 (0.58) BRD4MEN1KMT2AMAPK1POLB
SCHEMBL14010063 0.93 BRD4 (0.48) BRD4MEN1KMT2AMAPK1POLB
SCHEMBL11892525 0.91 BRD4 (0.50) BRD4MEN1KMT2AMAPK1POLB
SCHEMBL13533865 0.90 BRD4 (0.55) BRD4MEN1KMT2AMAPK1POLB
SCHEMBL7594849 0.90 MEN1 (0.54) BRD4MEN1KMT2APOLBLPAR1
SCHEMBL26030942 0.89 MEN1 (0.51) BRD4MEN1KMT2AMAPK1POLB
SCHEMBL13018340 0.88 MEN1 (0.53) BRD4MEN1KMT2APOLBLPAR1
SCHEMBL13018338 0.88 MEN1 (0.53) BRD4MEN1KMT2APOLBLPAR1
SCHEMBL13018341 0.88 MEN1 (0.53) BRD4MEN1KMT2APOLBLPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7445852-B2 Magnetic substrate, laminate of magnetic substrate and method for producing thereof MITSUI CHEMICALS, INC. (JP) 2008-11-04 US disclosed