Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 4/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | ADA | P00813 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | NT5E | P21589 | 2/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11896702 | 1.00 | ADORA2A (0.39) | ADORA2ASLC29A1PDE4DPDE3AADA | |
| SCHEMBL5006780 | 0.89 | ADORA2A (0.51) | ADORA2ASLC29A1PDE4DPDE3AADA | |
| SCHEMBL5009459 | 0.86 | ADORA2A (0.38) | ADORA2ASLC29A1PDE4DPDE3AADA | |
| SCHEMBL14036110 | 0.85 | ADORA2A (0.51) | ADORA2APRMT5WDR77ADK | |
| SCHEMBL14010191 | 0.85 | ADORA2A (0.51) | ADORA2APRMT5WDR77ADK | |
| SCHEMBL14036258 | 0.85 | ADORA2A (0.51) | ADORA2APRMT5WDR77ADK | |
| SCHEMBL14010192 | 0.81 | PDE4D (0.41) | ADORA2ASLC29A1PDE4DPDE3ALMNA | |
| SCHEMBL13929038 | 0.79 | ADORA2A (0.62) | ADORA2APDE4DPDE3AADACYP2C19 | |
| SCHEMBL465590 | 0.79 | ADORA2A (0.62) | ADORA2APDE4DPDE3AADACYP2C19 | |
| SCHEMBL20991001 | 0.79 | ADORA2A (0.62) | ADORA2APDE4DPDE3AADACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080280842-A1 | Fluorinated Pyrrolo[2,3-D]Pyrimidine Nucleosides for the Treatment of Rna-Dependent Rna Viral Infection | MERCK & CO., INC. (US) | 2008-11-13 | — | — | US | disclosed |
| US-20080280842-A1 | Fluorinated Pyrrolo[2,3-D]Pyrimidine Nucleosides for the Treatment of Rna-Dependent Rna Viral Infection | MERCK & CO., INC. (US) | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280842-A1 | Fluorinated Pyrrolo[2,3-D]Pyrimidine Nucleosides for the Treatment of Rna-Dependent Rna Viral Infection | NSUN2, DUT, EFTUD2 | ADORA2A 444/4885SLC29A1 112/4885PDE4D 650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.