Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 9/20 | 0.61 |
| ▸ | THRA | P10827 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | ACR | P10323 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12404405 | 0.97 | THRB (0.67) | THRBTHRAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL19930191 | 0.94 | THRB (0.64) | THRBTHRAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL12154170 | 0.93 | THRB (0.62) | THRBTHRAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL16657529 | 0.93 | THRB (0.64) | THRBTHRAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL14010349 | 0.93 | THRB (0.64) | THRBTHRAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL19930193 | 0.91 | THRB (0.56) | THRBTHRAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL19930205 | 0.91 | THRB (0.56) | THRBTHRAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL19930189 | 0.90 | THRB (0.51) | THRBMAPTSMN1; SMN2KMT2APRSS1 | |
| SCHEMBL12733830 | 0.90 | THRB (0.51) | THRBMAPTSMN1; SMN2KMT2APRSS1 | |
| SCHEMBL16379487 | 0.90 | THRB (0.60) | THRBTHRAMAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449223-B2 | containing an additive that improves the level of defects in the vicinity of the air interface for an optically anisotropic medium that exhibits either tilted alignment or horizontal alignment | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2008-11-11 | — | — | US | disclosed |
| US-20070170394-A1 | Polymerizable liquid crystal composition and optically anisotropic medium | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2007-07-26 | — | — | US | disclosed |