Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 6/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4970598 | 0.83 | AOC3 (0.53) | FFAR1FFAR4 | |
| SCHEMBL1400886 | 0.82 | KDM4E (0.39) | LTB4R2PTGS2 | |
| SCHEMBL5199653 | 0.76 | KMT2A (0.47) | FFAR1FFAR4 | |
| SCHEMBL4972529 | 0.74 | PTGER1 (0.43) | FFAR1LTB4R2 | |
| SCHEMBL68745 | 0.74 | FFAR1 (0.42) | FFAR1FFAR4RARBRARARARG | |
| SCHEMBL4971902 | 0.73 | AOC3 (0.60) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL4971682 | 0.72 | AOC3 (0.48) | — | |
| SCHEMBL7338362 | 0.72 | RARB (0.71) | FFAR1FFAR4RARBRARARARG | |
| SCHEMBL31270921 | 0.72 | RARB (0.71) | FFAR1FFAR4RARBRARARARG | |
| SCHEMBL4970822 | 0.72 | RARB (0.46) | FFAR1FFAR4LTB4R2RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814871-B1 | COMPOUNDS THAT MODULATE PPARY TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2011-03-02 | — | — | EP | disclosed |