Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4970598 | 0.84 | AOC3 (0.53) | KMT2AFFAR1FFAR4AOC3 | |
| SCHEMBL4968446 | 0.78 | FFAR1 (0.48) | KMT2AFFAR1FFAR4FOLH1AOC3 | |
| SCHEMBL4970077 | 0.77 | FAAH (0.46) | KMT2AFFAR1FFAR4FOLH1AOC3 | |
| SCHEMBL4970822 | 0.77 | RARB (0.46) | KMT2AFFAR1FFAR4 | |
| SCHEMBL1401140 | 0.76 | FFAR1 (0.45) | FFAR1FFAR4 | |
| SCHEMBL13639173 | 0.76 | NPC1 (0.53) | KMT2ANPC1RAB9AFOLH1BCHE | |
| SCHEMBL4970065 | 0.76 | FFAR1 (0.46) | KMT2AFFAR1FFAR4FOLH1AOC3 | |
| SCHEMBL4969532 | 0.75 | FFAR1 (0.44) | KMT2AFFAR1FFAR4FOLH1AOC3 | |
| SCHEMBL4969426 | 0.75 | FFAR1 (0.50) | PPARGFFAR1FFAR4BCHEACHE | |
| SCHEMBL4970418 | 0.75 | FFAR1 (0.42) | KMT2APPARGFFAR1FFAR4FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814871-A2 | COMPOUNDS THAT MODULATE PPARY TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006053791-A2 | COMPOUNDS THAT MODULATE PPARY TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2006-05-26 | — | — | WO | disclosed |