Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5049195 | 0.93 | PDK2 (0.42) | MAPTNPC1RAB9APDK2S100A4 | |
| SCHEMBL28656781 | 0.83 | HDAC3 (0.39) | MAPTNPC1RAB9APDK2TP53 | |
| SCHEMBL29294962 | 0.81 | PDK2 (0.37) | NPC1RAB9APDK2S100A4MEN1 | |
| SCHEMBL29375527 | 0.81 | PDK2 (0.39) | NPC1RAB9APDK2S100A4MEN1 | |
| SCHEMBL1993181 | 0.81 | PDK2 (0.39) | NPC1RAB9APDK2S100A4MEN1 | |
| SCHEMBL27584898 | 0.81 | MAPT (0.37) | MAPTTP53KMT2ASRD5A1SRD5A2 | |
| SCHEMBL17084359 | 0.81 | PDK2 (0.56) | MAPTNPC1RAB9APDK2S100A4 | |
| SCHEMBL18175540 | 0.78 | S100A4 (0.34) | S100A4CA1CA2CA4CA7 | |
| SCHEMBL4341387 | 0.77 | PDK2 (0.47) | MAPTPDK2MEN1KMT2AL3MBTL1 | |
| SCHEMBL29763208 | 0.77 | PDK2 (0.47) | MAPTPDK2MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7445825-B2 | Donor sheet having a polymerizable, amorphous matrix with electrically active material disposed therein | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-11-04 | — | — | US | disclosed |
| US-7445825-B2 | Donor sheet having a polymerizable, amorphous matrix with electrically active material disposed therein | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-11-04 | — | — | US | disclosed |