SCHEMBL1401307

SCHEMBL1401307

CN(C)CC1CCCN1C(=O)C(Cc1ccccc1)N(C)C(=O)C(Cc1ccc2ccccc2c1)N(C)C(=O)/C=C/CC(C)(C)NC(=O)OC(C)(C)C

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 7/20 0.51
TACR1 P25103 7/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1401212 1.00 GHSR (0.51) GHSRTACR1
SCHEMBL1401209 1.00 GHSR (0.51) GHSRTACR1
SCHEMBL1401113 0.89 GHSR (0.53) GHSRTACR1
SCHEMBL1401111 0.89 GHSR (0.53) GHSRTACR1
SCHEMBL1401167 0.89 GHSR (0.50) GHSRTACR1
SCHEMBL1401168 0.89 GHSR (0.50) GHSRTACR1
SCHEMBL1401165 0.89 GHSR (0.50) GHSRTACR1
SCHEMBL868029 0.88 GHSR (0.53) GHSRTACR1
SCHEMBL868030 0.88 GHSR (0.53) GHSRTACR1
SCHEMBL1401118 0.85 TACR1 (0.45) TACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1100824-B1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK AS (DK) 2011-03-02 EP disclosed