Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.54 |
| ▸ | RAB9A | P51151 | 8/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.54 |
| ▸ | TP53 | P04637 | 4/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12799393 | 0.93 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL1663386 | 0.91 | MEN1 (0.51) | NPC1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL14176439 | 0.85 | SMN1; SMN2 (0.50) | NPC1RAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL11303092 | 0.84 | CYP3A4 (0.60) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL14176438 | 0.83 | SMN1; SMN2 (0.51) | NPC1RAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL14176435 | 0.81 | MAPT (0.56) | NPC1RAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL10962287 | 0.81 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL14176441 | 0.80 | MAPT (0.55) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL14176440 | 0.80 | ABCB1 (0.55) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL31710349 | 0.79 | MEN1 (0.60) | NPC1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456188-B1 | C-5 substituted quinazolinone derivatives as selective estrogen receptor beta modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-11-25 | — | — | US | disclosed |