Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.73 |
| ▸ | HPGD | P15428 | 11/20 | 0.67 |
| ▸ | TSHR | P16473 | 6/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 2/20 | 0.54 |
| ▸ | CASP7 | P55210 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4211751 | 0.94 | KDM4E (0.77) | KDM4EHPGDTSHRTP53ALDH1A1 | |
| SCHEMBL14013253 | 0.93 | KDM4E (0.73) | KDM4EHPGDTSHRTP53ALDH1A1 | |
| SCHEMBL4200844 | 0.92 | ALDH1A1 (0.74) | KDM4EHPGDTSHRTP53ALDH1A1 | |
| SCHEMBL4203621 | 0.90 | ALDH1A1 (0.70) | KDM4EHPGDTSHRTP53ALDH1A1 | |
| SCHEMBL14013763 | 0.90 | KDM4E (0.69) | KDM4EHPGDTSHRTP53ALDH1A1 | |
| SCHEMBL14013857 | 0.90 | KDM4E (0.71) | KDM4EHPGDTSHRTP53ALDH1A1 | |
| SCHEMBL14013876 | 0.88 | KDM4E (0.67) | KDM4EHPGDTSHRTP53ALDH1A1 | |
| SCHEMBL4206709 | 0.87 | HPGD (0.77) | KDM4EHPGDTSHRTP53ALDH1A1 | |
| SCHEMBL14013218 | 0.87 | KDM4E (0.69) | KDM4EHPGDTSHRTP53ALDH1A1 | |
| SCHEMBL14013764 | 0.85 | ALDH1A1 (0.68) | KDM4EHPGDTSHRTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008134035-A1 | ALPHA-UNSUBSTITUTED ARYLMETHYL PIPERAZINE PYRAZOLO[1,5-A] PYRIMIDINE AMIDE DERIVATIVES | PANACOS PHARMACEUTICALS, INC. (US) | 2008-11-06 | — | — | WO | disclosed |