Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16676572 | 0.83 | PPARG (0.48) | PPARGRAB9AMAPTNPC1PPARA | |
| SCHEMBL8651094 | 0.81 | PPARG (0.50) | PPARGRAB9AMAPTNPC1PPARA | |
| SCHEMBL16666722 | 0.81 | PPARG (0.49) | PPARGRAB9AMAPTNPC1PPARA | |
| SCHEMBL5674725 | 0.81 | PPARG (0.50) | PPARGRAB9AMAPTNPC1PPARA | |
| SCHEMBL14038386 | 0.80 | ELANE (0.49) | PPARGPPARAHCRTR1HCRTR2 | |
| SCHEMBL14188640 | 0.79 | PPARG (0.57) | PPARGPPARA | |
| SCHEMBL6799513 | 0.79 | PPARG (0.48) | PPARGRAB9AMAPTNPC1PPARA | |
| SCHEMBL3105795 | 0.78 | PPARG (0.49) | PPARGRAB9AMAPTNPC1PPARA | |
| SCHEMBL6805662 | 0.78 | PPARG (0.47) | PPARGRAB9AMAPTNPC1PPARA | |
| SCHEMBL2541745 | 0.77 | PPARG (0.57) | PPARGPPARAHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456205-B2 | Benzopyran compounds, process for preparing the same and their use | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2008-11-25 | — | — | US | disclosed |