Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.59 |
| ▸ | ALPI | P09923 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | XIAP | P98170 | 1/20 | 0.59 |
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.50 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | TPH1 | P17752 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | NPY4R | P50391 | 3/20 | 0.44 |
| ▸ | NPY1R | P25929 | 2/20 | 0.44 |
| ▸ | NPY2R | P49146 | 2/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL4260597 | 1.00 | SLC7A5 (0.59) | SLC7A5ALPIPKMPTGS1XIAP | |
| Arginine SCHEMBL27641173 | 1.00 | SLC7A5 (0.59) | SLC7A5ALPIPKMPTGS1XIAP | |
| Arginine SCHEMBL27074661 | 1.00 | SLC7A5 (0.59) | SLC7A5ALPIPKMPTGS1XIAP | |
| Arginine SCHEMBL9482082 | 1.00 | SLC7A5 (0.59) | SLC7A5ALPIPKMPTGS1XIAP | |
| Arginine SCHEMBL4795238 | 1.00 | SLC7A5 (0.59) | SLC7A5ALPIPKMPTGS1XIAP | |
| Arginine SCHEMBL1537371 | 1.00 | SLC7A5 (0.59) | SLC7A5ALPIPKMPTGS1XIAP | |
| Arginine SCHEMBL2776813 | 1.00 | SLC7A5 (0.59) | SLC7A5ALPIPKMPTGS1XIAP | |
| Arginine SCHEMBL385198 | 1.00 | SLC7A5 (0.59) | SLC7A5ALPIPKMPTGS1XIAP | |
| Arginine SCHEMBL14861498 | 1.00 | SLC7A5 (0.59) | SLC7A5ALPIPKMPTGS1XIAP | |
| Arginine SCHEMBL28209520 | 0.99 | SLC7A5 (0.58) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024124258-A2 | METHODS OF PREPARING STABLE NUCLEIC ACID LIQUID FORMULATIONS | UNIVERSITY OF NORTH CAROLINA AT WILMINGTON (US) | 2024-06-13 | — | — | WO | claimed |
| US-20240191260-A1 | METHODS OF PREPARING STABLE NUCLEIC ACID LIQUID FORMULATIONS | UNIVERSITY OF NORTH CAROLINA AT WILMINGTON (US) | 2024-06-13 | — | — | US | claimed |
| CN-109134371-B | Fluorescence ratio probe, synthetic method thereof and application of fluorescence ratio probe in detecting intracellular lysosome formaldehyde | 东北大学 | 2020-07-10 | — | — | CN | claimed |
| EP-3148591-B1 | NANOPARTICLE DRUG CONJUGATES | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2020-03-11 | — | — | EP | claimed |
| US-20080261232-A1 | Use of Precursors of Enkephalins and/or Their Fragments in Medical Diagnostics | B.R.A.H.M.S AKTIENGESELLSCHAFT (DE) | 2008-10-23 | — | — | US | claimed |
| EP-1745297-A1 | USE OF PRECURSORS OF ENKEPHALINS AND/OR THEIR FRAGMENTS IN MEDICAL DIAGNOSTICS | SphingoTec GmbH (DE) | 2007-01-24 | — | — | EP | claimed |
| WO-2005114222-A1 | USE OF PRECURSORS OF ENKEPHALINS AND/OR THEIR FRAGMENTS IN MEDICAL DIAGNOSTICS | SPHINGO TEC GMBH (DE) | 2005-12-01 | — | — | WO | claimed |
| EP-0937139-A4 | AMIDASE | DIVERSA CORP (US) | 2000-08-02 | — | — | EP | claimed |
| EP-0937139-A1 | AMIDASE | DIVERSA CORPORATION (US) | 1999-08-25 | — | — | EP | claimed |
| WO-1997048794-A1 | AMIDASE | RECOMBINANT BIOCATALYSIS, INC. (US) | 1997-12-24 | — | — | WO | claimed |
| US-20240191260-A1 | METHODS OF PREPARING STABLE NUCLEIC ACID LIQUID FORMULATIONS | UNIVERSITY OF NORTH CAROLINA AT WILMINGTON (US) | 2024-06-13 | — | — | US | disclosed |
| WO-2024124258-A2 | METHODS OF PREPARING STABLE NUCLEIC ACID LIQUID FORMULATIONS | UNIVERSITY OF NORTH CAROLINA AT WILMINGTON (US) | 2024-06-13 | — | — | WO | disclosed |
| CN-118005913-A | Block copolymer with cell membrane pore-forming property and preparation method and application thereof | 四川大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-116459240-B | Application of KL-2 and derivatives thereof in preparation of antibacterial infection medicines | 华中科技大学协和深圳医院 | 2024-03-19 | — | — | CN | disclosed |
| CN-116459240-A | Application of KL-2 and derivatives thereof in preparation of antibacterial infection medicines | 华中科技大学协和深圳医院 | 2023-07-21 | — | — | CN | disclosed |
| CN-101214380-A | Method and carrier complexes for delivering molecules to cells | CORNELL RES FOUNDATION INC (US) | 2008-07-09 | — | — | CN | disclosed |
| CN-1950103-A | Method for preventing or treating bone diseases | METABOLIC PHARM LTD (AU) | 2007-04-18 | — | — | CN | disclosed |
| EP-1745297-A1 | USE OF PRECURSORS OF ENKEPHALINS AND/OR THEIR FRAGMENTS IN MEDICAL DIAGNOSTICS | SphingoTec GmbH (DE) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005114222-A1 | USE OF PRECURSORS OF ENKEPHALINS AND/OR THEIR FRAGMENTS IN MEDICAL DIAGNOSTICS | SPHINGO TEC GMBH (DE) | 2005-12-01 | — | — | WO | disclosed |
| WO-1999058640-A2 | MCT-1, A HUMAN ONCOGENE | PHILADELPHIA HEALTH AND EDUCATION CORPORATION (US) | 1999-11-18 | — | — | WO | disclosed |