Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.59 |
| ▸ | ALPI | P09923 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | XIAP | P98170 | 1/20 | 0.59 |
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.50 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | TPH1 | P17752 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | NPY4R | P50391 | 3/20 | 0.44 |
| ▸ | NPY1R | P25929 | 2/20 | 0.44 |
| ▸ | NPY2R | P49146 | 2/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL4260597 | 1.00 | SLC7A5 (0.59) | SLC7A5ALPIPKMPTGS1XIAP | |
| Arginine SCHEMBL1401438 | 1.00 | SLC7A5 (0.59) | SLC7A5ALPIPKMPTGS1XIAP | |
| Arginine SCHEMBL27641173 | 1.00 | SLC7A5 (0.59) | SLC7A5ALPIPKMPTGS1XIAP | |
| Arginine SCHEMBL27074661 | 1.00 | SLC7A5 (0.59) | SLC7A5ALPIPKMPTGS1XIAP | |
| Arginine SCHEMBL9482082 | 1.00 | SLC7A5 (0.59) | SLC7A5ALPIPKMPTGS1XIAP | |
| Arginine SCHEMBL4795238 | 1.00 | SLC7A5 (0.59) | SLC7A5ALPIPKMPTGS1XIAP | |
| Arginine SCHEMBL1537371 | 1.00 | SLC7A5 (0.59) | SLC7A5ALPIPKMPTGS1XIAP | |
| Arginine SCHEMBL2776813 | 1.00 | SLC7A5 (0.59) | SLC7A5ALPIPKMPTGS1XIAP | |
| Arginine SCHEMBL14861498 | 1.00 | SLC7A5 (0.59) | SLC7A5ALPIPKMPTGS1XIAP | |
| Arginine SCHEMBL28209520 | 0.99 | SLC7A5 (0.58) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024124258-A2 | METHODS OF PREPARING STABLE NUCLEIC ACID LIQUID FORMULATIONS | UNIVERSITY OF NORTH CAROLINA AT WILMINGTON (US) | 2024-06-13 | — | — | WO | claimed |
| US-20240191260-A1 | METHODS OF PREPARING STABLE NUCLEIC ACID LIQUID FORMULATIONS | UNIVERSITY OF NORTH CAROLINA AT WILMINGTON (US) | 2024-06-13 | — | — | US | claimed |
| US-11484607-B2 | PSMA-targeted NIR dyes and their uses | On Target Laboratories, LLC (US) | 2022-11-01 | — | — | US | claimed |
| CN-115025204-A | Dipeptide compound for inhibiting A beta 42 aggregation and reducing cytotoxic effect thereof | 王大勇 | 2022-09-09 | — | — | CN | claimed |
| CN-113559054-A | Active oxygen scavenging/responding allosteric self-assembly hydrogel and application thereof | 南京工业大学 | 2021-10-29 | — | — | CN | claimed |
| WO-2021140343-A1 | LIGAND DRUG CONJUGATES AND MODIFIED BET INHIBITORS | HOVIONE SCIENTIA LIMITED (IE) | 2021-07-15 | — | — | WO | claimed |
| CN-113082225-A | Nanoparticle drug conjugates | 纪念斯隆-凯特琳癌症中心 | 2021-07-09 | — | — | CN | claimed |
| CN-106659797-B | Nanoparticle drug conjugates | 纪念斯隆-凯特琳癌症中心 | 2021-04-27 | — | — | CN | claimed |
| US-20210046194-A1 | PSMA-TARGETED NIR DYES AND THEIR USES | On Target Laboratories, Inc. | 2021-02-18 | — | — | US | claimed |
| CN-107106992-B | Hybrid filter construction for filtering liquids | 韩国机械研究院 | 2020-08-21 | — | — | CN | claimed |
| WO-2010040024-A2 | METHODS, COMPOSITIONS AND KITS FOR HIGH THROUGHPUT KINASE ACTIVITY SCREENING USING MASS SPECTROMETRY AND STABLE ISOTOPES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-04-08 | — | — | WO | claimed |
| US-20080261232-A1 | Use of Precursors of Enkephalins and/or Their Fragments in Medical Diagnostics | B.R.A.H.M.S AKTIENGESELLSCHAFT (DE) | 2008-10-23 | — | — | US | claimed |
| EP-1745297-A1 | USE OF PRECURSORS OF ENKEPHALINS AND/OR THEIR FRAGMENTS IN MEDICAL DIAGNOSTICS | SphingoTec GmbH (DE) | 2007-01-24 | — | — | EP | claimed |
| WO-2005114222-A1 | USE OF PRECURSORS OF ENKEPHALINS AND/OR THEIR FRAGMENTS IN MEDICAL DIAGNOSTICS | SPHINGO TEC GMBH (DE) | 2005-12-01 | — | — | WO | claimed |
| EP-1064010-A4 | PEPTIDE COMPOSITIONS AND FORMULATIONS AND USE OF SAME | CONNECTIVE TISSUE IMAGINEERING (US) | 2004-10-06 | — | — | EP | claimed |
| EP-1064010-A1 | PEPTIDE COMPOSITIONS AND FORMULATIONS AND USE OF SAME | Mrs, Llc (US) | 2001-01-03 | — | — | EP | claimed |
| EP-0937139-A4 | AMIDASE | DIVERSA CORP (US) | 2000-08-02 | — | — | EP | claimed |
| WO-1999045941-A1 | PEPTIDE COMPOSITIONS AND FORMULATIONS AND USE OF SAME | MRS, LLC (US) | 1999-09-16 | — | — | WO | claimed |
| EP-0937139-A1 | AMIDASE | DIVERSA CORPORATION (US) | 1999-08-25 | — | — | EP | claimed |
| WO-1997048794-A1 | AMIDASE | RECOMBINANT BIOCATALYSIS, INC. (US) | 1997-12-24 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210046194-A1 | PSMA-TARGETED NIR DYES AND THEIR USES | KLK3, FOLH1, CD47 | SLC7A5 854/4885ALPI 447/4885PKM 892/4885 |
| US-11484607-B2 | PSMA-targeted NIR dyes and their uses | KLK3, FOLH1, CD47 | SLC7A5 854/4885ALPI 447/4885PKM 892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.