Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22738295 | 0.75 | KMT2A (0.52) | KMT2AALDH1A1MAPK1MAOBMAPT | |
| SCHEMBL14015237 | 0.74 | ALDH1A1 (0.58) | KMT2AALDH1A1MAPK1MAOBMAPT | |
| SCHEMBL13961845 | 0.72 | KMT2A (0.56) | KMT2AALDH1A1MAPK1MAOBMAPT | |
| SCHEMBL13988542 | 0.71 | KMT2A (0.43) | KMT2AALDH1A1MAPK1MAOBMAPT | |
| SCHEMBL11468890 | 0.70 | ALDH1A1 (0.56) | KMT2AALDH1A1MAPK1MAOBMAPT | |
| SCHEMBL11468858 | 0.69 | ALDH1A1 (0.51) | KMT2AALDH1A1MAPK1MAOBMAPT | |
| SCHEMBL13988528 | 0.69 | KMT2A (0.50) | KMT2AALDH1A1MAPK1MAOBMAPT | |
| SCHEMBL13988492 | 0.68 | KMT2A (0.52) | KMT2AALDH1A1MAPK1MAOBMAPT | |
| SCHEMBL8517287 | 0.67 | KMT2A (0.64) | KMT2AALDH1A1MAPK1MAOBMAPT | |
| SCHEMBL13988533 | 0.66 | KMT2A (0.50) | KMT2AALDH1A1MAPK1MAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442689-B2 | Cardioprotective phosphonates and malonates | MEDICURE INTERNATIONAL INC. (BB) | 2008-10-28 | — | — | US | disclosed |
| US-7442689-B2 | Cardioprotective phosphonates and malonates | MEDICURE INTERNATIONAL INC. (BB) | 2008-10-28 | — | — | US | disclosed |