Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 8/20 | 0.66 |
| ▸ | CTSK | P43235 | 1/20 | 0.57 |
| ▸ | BAZ2B | Q9UIF8 | 9/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14015613 | 0.84 | BAZ2B (0.77) | CFTRCTSKBAZ2BSMN1; SMN2 | |
| SCHEMBL5107538 | 0.83 | CFTR (0.61) | CFTRCTSKBAZ2BTRPV1LMNA | |
| SCHEMBL23828222 | 0.80 | CFTR (1.00) | CFTR | |
| SCHEMBL31020945 | 0.80 | CFTR (1.00) | CFTR | |
| SCHEMBL5376181 | 0.80 | TRPV1 (0.66) | CFTRCTSKTRPV1 | |
| SCHEMBL2189728 | 0.79 | L3MBTL1 (0.65) | CFTR | |
| SCHEMBL14015615 | 0.78 | MAPT (0.75) | CFTRBAZ2BLMNAATM | |
| SCHEMBL31117487 | 0.76 | TRPV1 (0.62) | CFTRTRPV1 | |
| SCHEMBL31020940 | 0.76 | CFTR (0.61) | CFTRBAZ2BLMNAPABPC1ATM | |
| SCHEMBL23828211 | 0.76 | CFTR (0.61) | CFTRBAZ2BLMNAPABPC1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449476-B2 | Tetrahydrocarboline antiviral agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-11-11 | — | — | US | disclosed |