Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 12/20 | 0.62 |
| ▸ | TUBB4A | P04350 | 11/20 | 0.62 |
| ▸ | TUBB | P07437 | 11/20 | 0.62 |
| ▸ | TUBA3C | P0DPH7 | 11/20 | 0.62 |
| ▸ | TUBA1B | P68363 | 11/20 | 0.62 |
| ▸ | TUBA4A | P68366 | 11/20 | 0.62 |
| ▸ | TUBB4B | P68371 | 11/20 | 0.62 |
| ▸ | TUBB3 | Q13509 | 11/20 | 0.62 |
| ▸ | TUBB2A | Q13885 | 11/20 | 0.62 |
| ▸ | TUBB8 | Q3ZCM7 | 11/20 | 0.62 |
| ▸ | TUBA3E | Q6PEY2 | 11/20 | 0.62 |
| ▸ | TUBA1A | Q71U36 | 11/20 | 0.62 |
| ▸ | TUBA1C | Q9BQE3 | 11/20 | 0.62 |
| ▸ | TUBB6 | Q9BUF5 | 11/20 | 0.62 |
| ▸ | TUBB2B | Q9BVA1 | 11/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1401446 | 0.89 | TUBB4A (0.68) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1401581 | 0.85 | TUBB1 (0.65) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1401779 | 0.85 | TUBB1 (0.64) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1401568 | 0.84 | TUBB4A (0.66) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1401579 | 0.84 | TUBB1 (0.63) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1401580 | 0.84 | TUBB1 (0.63) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1401443 | 0.83 | TUBB4A (0.73) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13622251 | 0.82 | TUBB4A (0.69) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1401524 | 0.82 | TUBB4A (0.63) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1401518 | 0.81 | TUBB4A (0.76) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646608-B1 | TRICYCLIC DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, THEIR PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | JE IL PHARMACEUTICAL CO LTD (KR) | 2011-03-02 | — | — | EP | claimed |