Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 5/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.34 |
| ▸ | RELA | Q04206 | 3/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14015843 | 0.94 | EPHX2 (0.40) | EPHX2ATMPYGLDRD2KDM1A | |
| SCHEMBL13299034 | 0.85 | EPHX2 (0.47) | EPHX2ATMPYGLDRD2KDM1A | |
| SCHEMBL13299015 | 0.85 | EPHX2 (0.47) | EPHX2ATMPYGLDRD2KDM1A | |
| SCHEMBL4653880 | 0.84 | EPHX2 (0.43) | EPHX2ATMPYGLDRD2KDM1A | |
| SCHEMBL4653995 | 0.83 | PYGL (0.48) | ATMPYGLKMT2A | |
| SCHEMBL4653994 | 0.83 | PYGL (0.48) | ATMPYGLKMT2A | |
| SCHEMBL14143108 | 0.83 | ATM (0.47) | EPHX2ATMDRD2KDM1AMAOB | |
| SCHEMBL3328981 | 0.80 | PYGL (0.49) | EPHX2ATMPYGLDRD2KDM1A | |
| SCHEMBL13299051 | 0.79 | EPHX2 (0.44) | EPHX2ATMPYGLDRD2KDM1A | |
| SCHEMBL8652209 | 0.79 | KMT2A (0.46) | EPHX2ATMDRD2KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658067-B1 | INDOLAMIDE DERIVATIVES WHICH POSSESS GLYCOGEN PHOSPHORYLASE INHIBITORY ACTIVITY | ASTRAZENECA AB (SE) | 2008-11-12 | — | — | EP | disclosed |