Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.45 |
| ▸ | RAB9A | P51151 | 10/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11733969 | 0.99 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2HPGDKDM4E | |
| SCHEMBL11738096 | 0.97 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2HPGDKDM4E | |
| SCHEMBL11738088 | 0.97 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2HPGDKDM4E | |
| SCHEMBL11733977 | 0.93 | SMN1; SMN2 (0.40) | NPC1RAB9ASMN1; SMN2HPGDKDM4E | |
| SCHEMBL10766985 | 0.88 | KDM4E (0.44) | NPC1RAB9ASMN1; SMN2HPGDKDM4E | |
| SCHEMBL11499348 | 0.86 | KDM4E (0.43) | RAB9ASMN1; SMN2KDM4EHSD17B10RELA | |
| SCHEMBL11125994 | 0.86 | KDM4E (0.43) | NPC1RAB9ASMN1; SMN2HPGDKDM4E | |
| SCHEMBL11499347 | 0.86 | KDM4E (0.43) | RAB9ASMN1; SMN2KDM4EHSD17B10RELA | |
| SCHEMBL6395530 | 0.86 | KDM4E (0.43) | NPC1RAB9ASMN1; SMN2HPGDKDM4E | |
| SCHEMBL11682761 | 0.86 | KDM4E (0.43) | NPC1RAB9ASMN1; SMN2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7438898-B1 | Hair conditioning composition comprising carboxylic acid/carboxylate copolymer, and visible particle | THE PROCTER & GAMBLE COMPANY (US) | 2008-10-21 | — | — | US | disclosed |