Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11499347 | 1.00 | KDM4E (0.43) | KDM4EHSD17B10P2RX7CYP11B1CYP11B2 | |
| SCHEMBL10766985 | 0.95 | KDM4E (0.44) | KDM4EHSD17B10P2RX7CYP11B1CYP11B2 | |
| SCHEMBL11682761 | 0.94 | KDM4E (0.43) | KDM4EHSD17B10P2RX7CYP11B1CYP11B2 | |
| SCHEMBL11125994 | 0.94 | KDM4E (0.43) | KDM4EHSD17B10P2RX7CYP11B1CYP11B2 | |
| SCHEMBL6395530 | 0.94 | KDM4E (0.43) | KDM4EHSD17B10P2RX7CYP11B1CYP11B2 | |
| SCHEMBL14016644 | 0.86 | NPC1 (0.45) | KDM4EHSD17B10MEN1KMT2ARELA | |
| SCHEMBL11733969 | 0.85 | NPC1 (0.44) | KDM4EHSD17B10MEN1KMT2ARELA | |
| SCHEMBL186881 | 0.84 | KDM4E (0.51) | KDM4EHSD17B10P2RX7MEN1KMT2A | |
| SCHEMBL11738088 | 0.83 | NPC1 (0.45) | KDM4EHSD17B10P2RX7MEN1KMT2A | |
| SCHEMBL11738096 | 0.83 | NPC1 (0.45) | KDM4EHSD17B10P2RX7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235741-A | OPTICAL BRIGHTENERS OF 2,4-BIS-(STILBEN-4'-YL)-V-TRIAZOLES | CIBA-GEIGY CORPORATION (US) | 1980-11-25 | — | — | US | disclosed |