Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.35 |
| ▸ | DUT | P33316 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.33 |
| ▸ | P2RY2 | P41231 | 7/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | P2RY4 | P51582 | 5/20 | 0.31 |
| ▸ | POLA1 | P09884 | 1/20 | 0.31 |
| ▸ | P2RY6 | Q15077 | 6/20 | 0.30 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.30 |
| ▸ | P2RX6 | O15547 | 1/20 | 0.30 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.30 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14400570 | 1.00 | RNASE1 (0.35) | RNASE1DUTPOLBP2RX3P2RX4 | |
| SCHEMBL13614575 | 0.79 | P2RY2 (0.55) | RNASE1DUTPOLBP2RX3P2RX4 | |
| SCHEMBL16325834 | 0.74 | POLB (0.52) | POLBP2RY2P2RY4P2RY6 | |
| SCHEMBL13614916 | 0.74 | POLB (0.52) | POLBP2RY2P2RY4P2RY6 | |
| SCHEMBL13614480 | 0.65 | RNASE1 (0.35) | RNASE1DUTPOLB | |
| SCHEMBL13614865 | 0.65 | RNASE1 (0.35) | RNASE1DUTPOLB | |
| SCHEMBL13614535 | 0.64 | POLB (0.60) | DUTPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL14017366 | 0.64 | POLB (0.60) | DUTPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL13614439 | 0.64 | RNASE1 (0.36) | RNASE1POLBP2RX3P2RX4P2RX2 | |
| SCHEMBL14017199 | 0.64 | RNASE1 (0.36) | RNASE1POLBP2RX3P2RX4P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435724-B2 | Degradation-resistant mononucleoside phosphate compounds | INSPIRE PHARMACEUTICAL, INC. (US) | 2008-10-14 | — | — | US | disclosed |
| US-20070244068-A1 | Degradation-resistant mononucleoside phosphate compounds | INSPIRE PHARMACEUTICALS, INC. | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244068-A1 | Degradation-resistant mononucleoside phosphate compounds | PNKP, ENTPD5, ENPP1 | RNASE1 147/4885DUT 58/4885POLB 160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.