SCHEMBL140183

SCHEMBL140183

C=CCCCCC1CC2C=CC1C2

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.37
ALDH1A1 P00352 2/20 0.37
TSHR P16473 1/20 0.33
MEN1 O00255 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1244694 0.98 KDM4E (0.36) KDM4EALDH1A1TSHRMEN1HTT
SCHEMBL140083 0.98 KDM4E (0.36) KDM4EALDH1A1TSHRMEN1HTT
SCHEMBL143886 0.95 KDM4E (0.38) KDM4EALDH1A1TSHRMEN1HTT
SCHEMBL134022 0.87 KDM4E (0.40) KDM4EALDH1A1TSHRMEN1HTT
SCHEMBL1975023 0.84 KDM4E (0.46) KDM4EALDH1A1TSHRMEN1HTT
SCHEMBL4445579 0.82 KDM4E (0.44) KDM4EALDH1A1TSHRMEN1HTT
SCHEMBL30996063 0.82 KDM4E (0.44) KDM4EALDH1A1TSHRMEN1HTT
SCHEMBL3682573 0.82 KDM4E (0.37) KDM4EALDH1A1TSHRMEN1HTT
SCHEMBL13346689 0.81 KDM4E (0.36) KDM4EALDH1A1TSHRMEN1HTT
SCHEMBL465885 0.81 KDM4E (0.36) KDM4EALDH1A1TSHRMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 655 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388744-A1 HALOGEN FREE AND PHOSPHORUS FREE LOW LOSS FLAME RETARDANT COMPOSITIONS CONTAINING POLYCYCLIC-OLEFINIC POLYMER WITH OLEFINIC AND ANHYDRIDE FUNCTIONALITY AND MELAMINE PROMERUS, LLC (US) 2025-12-25 US claimed
EP-4584310-A1 H-BORON NITRIDE AND POLYCYCLIC-OLEFINIC POLYMER CONTAINING OLEFINIC FUNCTIONALITY FOR FORMING LOW-LOSS FILMS HAVING IMPROVED DIELECTRIC AND THERMAL PROPERTIES Promerus, LLC (US) 2025-07-16 EP claimed
EP-4584308-A1 POLYCYCLIC-OLEFINIC POLYMERS CONTAINING OLEFINIC FUNCTIONALITY FOR FORMING LOW-LOSS FILMS HAVING IMPROVED THERMAL PROPERTIES Promerus, LLC (US) 2025-07-16 EP claimed
EP-4584309-A1 POLYCYCLIC-OLEFINIC POLYMERS CONTAINING ACRYLATE FUNCTIONALITY WITH ACRYLATE/MALEIMIDE CROSSLINKERS AS B-STAGEABLE COMPOSITIONS FOR LOW LOSS APPLICATIONS Promerus, LLC (US) 2025-07-16 EP claimed
EP-4584324-A1 FLAME RETARDANT COMPOSITIONS CONTAINING POLYCYCLIC-OLEFINIC POLYMER WITH OLEFINIC FUNCTIONALITY FOR FORMING LOW-LOSS FILMS HAVING IMPROVED DIELECTRIC AND THERMAL PROPERTIES Promerus, LLC (US) 2025-07-16 EP claimed
CN-119998382-A Flame retardant compositions comprising polycycloolefinic polymers containing olefinic functionality for forming low loss films with improved dielectric and thermal properties 普罗米鲁斯有限责任公司 2025-05-13 CN claimed
CN-119968406-A Polycyclic olefin polymers containing acrylate functionality and acrylate/maleimide crosslinkers as B-stageable compositions in low loss applications 普罗米鲁斯有限责任公司 2025-05-09 CN claimed
US-20240141087-A1 POLYCYCLIC-OLEFINIC POLYMERS CONTAINING ACRYLATE FUNCTIONALITY WITH ACRYLATE/MALEIMIDE CROSSLINKERS AS B-STAGEABLE COMPOSITIONS FOR LOW LOSS APPLICATIONS PROMERUS, LLC (US) 2024-05-02 US claimed
US-20240109994-A1 POLYCYCLIC-OLEFINIC POLYMERS CONTAINING OLEFINIC FUNCTIONALITY FOR FORMING LOW-LOSS FILMS HAVING IMPROVED THERMAL PROPERTIES PROMERUS, LLC (US) 2024-04-04 US claimed
US-20240110003-A1 FLAME RETARDANT COMPOSITIONS CONTAINING POLYCYCLIC-OLEFINIC POLYMER WITH OLEFINIC FUNCTIONALITY FOR FORMING LOW-LOSS FILMS HAVING IMPROVED DIELECTRIC AND THERMAL PROPERTIES PROMERUS, LLC (US) 2024-04-04 US claimed
WO-2005061624-A1 BITUMINOUS COMPOSITIONS, METHOD FOR PRODUCING THE SAME, AND ROAD MATERIAL TOTAL FRANCE (FR) 2005-07-07 WO claimed
EP-1082368-B1 ROOF SHEETING UNIROYAL CHEM CO INC (US) 2004-10-20 EP claimed
EP-0870777-B1 Initiator system and process for the anionic (co)polymerisation of (meth)acrylic, vinylaromatic and/or dienic monomers ATOFINA (FR) 2003-09-24 EP claimed
US-6543199-B1 Ethylene-propylene-non-conjugated diene terpolymer; applying layers, overlapping, curing UNIROYAL CHEMICAL COMPANY, INC. 2003-04-08 US claimed
US-20010018397-A1 Comprising reaction product of a cyclic siloxane and an organometallic compound such as sec-butyllithium; for making polymethyl methacrylate with high content of isotactic triads ELF ATOCHEM S.A. (FR) 2001-08-30 US claimed
US-6136883-A POLYESTERURETHANE COPOLYMERS CRAY VALLEY S.A. (FR) 2000-10-24 US claimed
US-5851667-A Process for production of a composite product CRAY VALLEY S.A. (FR) 1998-12-22 US claimed
EP-0870777-A2 Initiator system and process for the anionic (co)polymerisation of (meth)acrylic, vinylaromatic and/or dienic monomers ELF ATOCHEM S.A. (FR) 1998-10-14 EP claimed
US-5288808-A Random, telechelic polymers having vinyl or diene sequences ATOCHEM (FR) 1994-02-22 US claimed
US-4469847-A IN PRESENCE OF ETHYLENE-PROPYLENE-DIENE TERPOLYMER SOCIETE CHIMIQUES DES CHARBONNAGES (FR) 1984-09-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388744-A1 HALOGEN FREE AND PHOSPHORUS FREE LOW LOSS FLAME RETARDANT COMPOSITIONS CONTAINING POLYCYCLIC-OLEFINIC POLYMER WITH OLEFINIC AND ANHYDRIDE FUNCTIONALITY AND MELAMINE PYM1, TAAR1, RAD52 KDM4E 745/4885ALDH1A1 2254/4885TSHR 383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.