SCHEMBL134022

SCHEMBL134022

C=CCCC1CC2C=CC1C2

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.40
ALDH1A1 P00352 3/20 0.40
TSHR P16473 1/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465884 0.89 KDM4E (0.36) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL465885 0.89 KDM4E (0.36) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL143886 0.89 KDM4E (0.38) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL140183 0.87 KDM4E (0.37) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL1244694 0.85 KDM4E (0.36) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL140083 0.85 KDM4E (0.36) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL1012047 0.80 KDM4E (0.48) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL3677071 0.80 KDM4E (0.40) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL141970 0.79 KDM4E (0.42) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL19467704 0.77 KDM4E (0.41) KDM4EALDH1A1TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 440 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388744-A1 HALOGEN FREE AND PHOSPHORUS FREE LOW LOSS FLAME RETARDANT COMPOSITIONS CONTAINING POLYCYCLIC-OLEFINIC POLYMER WITH OLEFINIC AND ANHYDRIDE FUNCTIONALITY AND MELAMINE PROMERUS, LLC (US) 2025-12-25 US claimed
EP-4584309-A1 POLYCYCLIC-OLEFINIC POLYMERS CONTAINING ACRYLATE FUNCTIONALITY WITH ACRYLATE/MALEIMIDE CROSSLINKERS AS B-STAGEABLE COMPOSITIONS FOR LOW LOSS APPLICATIONS Promerus, LLC (US) 2025-07-16 EP claimed
EP-4584310-A1 H-BORON NITRIDE AND POLYCYCLIC-OLEFINIC POLYMER CONTAINING OLEFINIC FUNCTIONALITY FOR FORMING LOW-LOSS FILMS HAVING IMPROVED DIELECTRIC AND THERMAL PROPERTIES Promerus, LLC (US) 2025-07-16 EP claimed
EP-4584324-A1 FLAME RETARDANT COMPOSITIONS CONTAINING POLYCYCLIC-OLEFINIC POLYMER WITH OLEFINIC FUNCTIONALITY FOR FORMING LOW-LOSS FILMS HAVING IMPROVED DIELECTRIC AND THERMAL PROPERTIES Promerus, LLC (US) 2025-07-16 EP claimed
EP-4584308-A1 POLYCYCLIC-OLEFINIC POLYMERS CONTAINING OLEFINIC FUNCTIONALITY FOR FORMING LOW-LOSS FILMS HAVING IMPROVED THERMAL PROPERTIES Promerus, LLC (US) 2025-07-16 EP claimed
CN-119998382-A Flame retardant compositions comprising polycycloolefinic polymers containing olefinic functionality for forming low loss films with improved dielectric and thermal properties 普罗米鲁斯有限责任公司 2025-05-13 CN claimed
CN-119968406-A Polycyclic olefin polymers containing acrylate functionality and acrylate/maleimide crosslinkers as B-stageable compositions in low loss applications 普罗米鲁斯有限责任公司 2025-05-09 CN claimed
US-20240141087-A1 POLYCYCLIC-OLEFINIC POLYMERS CONTAINING ACRYLATE FUNCTIONALITY WITH ACRYLATE/MALEIMIDE CROSSLINKERS AS B-STAGEABLE COMPOSITIONS FOR LOW LOSS APPLICATIONS PROMERUS, LLC (US) 2024-05-02 US claimed
US-20240110038-A1 h-BORON NITRIDE AND POLYCYCLIC-OLEFINIC POLYMER CONTAINING OLEFINIC FUNCTIONALITY FOR FORMING LOW-LOSS FILMS HAVING IMPROVED DIELECTRIC AND THERMAL PROPERTIES PROMERUS, LLC (US) 2024-04-04 US claimed
US-20240110003-A1 FLAME RETARDANT COMPOSITIONS CONTAINING POLYCYCLIC-OLEFINIC POLYMER WITH OLEFINIC FUNCTIONALITY FOR FORMING LOW-LOSS FILMS HAVING IMPROVED DIELECTRIC AND THERMAL PROPERTIES PROMERUS, LLC (US) 2024-04-04 US claimed
US-20160152796-A1 OIL EXTENDED ETHYLENE-ALPHA-OLEFIN-NON-CONJUGATED DIENE COPOLYMER ARLANXEO NETHERLANDS B.V. (NL) 2016-06-02 US claimed
US-20160147145-A1 PHOTOIMAGEABLE COMPOSITIONS CONTAINING OXETANE FUNCTIONALITY PROMERUS, LLC 2016-05-26 US claimed
WO-2016049123-A1 DIAZIRINE COMPOUNDS AS PHOTOCROSSLINKERS AND PHOTOIMAGEABLE COMPOSITIONS COMPRISING THEM PROMERUS, LLC (US) 2016-03-31 WO claimed
US-20160083352-A1 DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM SUMITOMO BAKELITE CO., LTD. (JP) 2016-03-24 US claimed
CN-105339426-A Oil-extended ethylene-alpha-olefin-non-conjugated diene copolymer LANXESS ELASTOMERS BV 2016-02-17 CN claimed
EP-2818513-B1 Oil extended ethylene-alpha-olefin-non-conjugated diene copolymer LANXESS ELASTOMERS BV (NL) 2015-12-23 EP claimed
WO-2014206952-A1 OIL EXTENDED ETHYLENE-ALPHA-OLEFIN-NON-CONJUGATED DIENE COPOLYMER LANXESS ELASTOMERS B.V. (NL) 2014-12-31 WO claimed
EP-2818513-A1 Oil extended ethylene-alpha-olefin-non-conjugated diene copolymer Lanxess Elastomers B.V. (NL) 2014-12-31 EP claimed
US-8530550-B2 Crosslinkable rubber composition MITSUI CHEMICALS, INC. (JP) 2013-09-10 US claimed
EP-0366411-A2 Graft polymers of ethylene-propylene-diene monomer polymers with propylene, means of preparation, and use of polypropylene compositions EXXON CHEMICAL PATENTS INC. (US) 1990-05-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160083352-A1 DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM RDX, AOX1, ALDH1A2 KDM4E 2719/4885ALDH1A1 24/4885TSHR 2733/4885
US-20250388744-A1 HALOGEN FREE AND PHOSPHORUS FREE LOW LOSS FLAME RETARDANT COMPOSITIONS CONTAINING POLYCYCLIC-OLEFINIC POLYMER WITH OLEFINIC AND ANHYDRIDE FUNCTIONALITY AND MELAMINE PYM1, TAAR1, RAD52 KDM4E 745/4885ALDH1A1 2254/4885TSHR 383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.