Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21002124 | 0.81 | TAAR1 (0.69) | AOC3HDAC1HDAC6CHRM2CHRM1 | |
| SCHEMBL14018571 | 0.80 | PPARA (0.50) | CYP2D6 | |
| SCHEMBL26613652 | 0.80 | TAAR1 (0.63) | AOC3CHRM2CHRM1CHRM3TAAR1 | |
| SCHEMBL21594142 | 0.80 | TAAR1 (0.63) | AOC3CHRM2CHRM1CHRM3TAAR1 | |
| SCHEMBL26628603 | 0.80 | TAAR1 (0.63) | AOC3CHRM2CHRM1CHRM3TAAR1 | |
| SCHEMBL14668122 | 0.79 | CHRM2 (0.59) | AOC3HDAC1HDAC6CHRM2CHRM1 | |
| SCHEMBL21002162 | 0.79 | TAAR1 (0.71) | AOC3HDAC1HDAC6CHRM2CHRM1 | |
| SCHEMBL20124013 | 0.78 | PPARA (0.51) | HDAC1HDAC6CHRM2CHRM1CHRM3 | |
| SCHEMBL555038 | 0.76 | AOC3 (0.66) | AOC3HDAC1HDAC6CHRM2CHRM1 | |
| SCHEMBL11991410 | 0.76 | TAAR1 (0.62) | AOC3CHRM2CHRM1CHRM3TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1988398-A1 | Immunoassay for tramadol and its major metabolites | Randox Laboratories Ltd. (GB) | 2008-11-05 | — | — | EP | disclosed |