Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.47 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | PTGIR | P43119 | 1/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | CSF3R | Q99062 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14018573 | 0.80 | AOC3 (0.50) | CYP2D6 | |
| SCHEMBL4112790 | 0.77 | PPARA (0.74) | PPARAPPARGCNR1CNR2CYP2D6 | |
| SCHEMBL25456613 | 0.77 | PPARA (0.74) | PPARAPPARGCNR1CNR2CYP2D6 | |
| SCHEMBL27419819 | 0.77 | PPARA (0.74) | PPARAPPARGCNR1CNR2CYP2D6 | |
| SCHEMBL4123448 | 0.77 | PPARA (0.74) | PPARAPPARGCNR1CNR2CYP2D6 | |
| SCHEMBL20945377 | 0.76 | PPARA (0.58) | PPARAPPARGPTGDR2PTGDRCNR1 | |
| SCHEMBL947863 | 0.76 | FFAR1 (0.67) | PPARAPPARGPTGDR2PTGDRCNR1 | |
| SCHEMBL26206374 | 0.75 | PPARA (0.51) | PPARAPPARGPTGDR2PTGDRCNR1 | |
| SCHEMBL7474979 | 0.74 | CYSLTR2 (0.57) | PPARAPPARGPTGDR2PTGDRCNR1 | |
| SCHEMBL27565591 | 0.74 | PPARA (0.55) | PPARAPPARGPTGDR2PTGDRCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1988398-A1 | Immunoassay for tramadol and its major metabolites | Randox Laboratories Ltd. (GB) | 2008-11-05 | — | — | EP | disclosed |