Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 3/20 | 0.62 |
| ▸ | AXL | P30530 | 3/20 | 0.61 |
| ▸ | MET | P08581 | 11/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14019018 | 1.00 | FGFR2 (0.62) | FGFR2AXLMETKDREGFR | |
| SCHEMBL2746450 | 0.91 | FGFR2 (0.54) | FGFR2AXLMETKDREGFR | |
| SCHEMBL2746454 | 0.91 | FGFR2 (0.54) | FGFR2AXLMETKDREGFR | |
| SCHEMBL4549044 | 0.91 | FGFR2 (0.54) | FGFR2AXLMETKDREGFR | |
| SCHEMBL2747557 | 0.89 | AXL (0.64) | FGFR2AXLMETKDREGFR | |
| SCHEMBL2747199 | 0.88 | FGFR2 (0.62) | FGFR2AXLMETKDREGFR | |
| SCHEMBL2747197 | 0.88 | FGFR2 (0.62) | FGFR2AXLMETKDREGFR | |
| SCHEMBL10280582 | 0.88 | FGFR2 (0.62) | FGFR2AXLMETKDREGFR | |
| SCHEMBL2748886 | 0.84 | AXL (0.86) | FGFR2AXLMETKDR | |
| SCHEMBL2747085 | 0.79 | MET (0.61) | FGFR2AXLMETKDREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435823-B2 | Compounds and methods of use | AMGEN INC. (US) | 2008-10-14 | — | — | US | disclosed |
| US-7435823-B2 | Compounds and methods of use | AMGEN INC. (US) | 2008-10-14 | — | — | US | disclosed |