Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.49 |
| ▸ | PTPN5 | P54829 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14019111 | 0.95 | NPC1 (0.71) | NPC1PTGS2PTPN2PTPN1PTPN5 | |
| SCHEMBL24037825 | 0.81 | NPC1 (0.51) | NPC1HPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL14019144 | 0.81 | NPC1 (0.62) | NPC1HPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL17691907 | 0.80 | NPC1 (0.56) | NPC1HPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL19846119 | 0.80 | NPC1 (0.63) | NPC1HPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL24037815 | 0.80 | PTPN2 (0.53) | NPC1PTPN2PTPN1PTPN5HPGD | |
| SCHEMBL24038098 | 0.79 | NPC1 (0.49) | NPC1PTPN2PTPN1PTPN5HPGD | |
| SCHEMBL17691817 | 0.79 | NPC1 (0.54) | NPC1HPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL28436509 | 0.79 | NPC1 (1.00) | NPC1PTGS2PTPN2PTPN1PTPN5 | |
| SCHEMBL14981161 | 0.78 | MAPT (0.59) | HPGDKDM4EALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442447-B2 | Binaphthol based chromophores for the fabrication of blue organic light emitting diodes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-10-28 | — | — | US | disclosed |
| US-7442447-B2 | Binaphthol based chromophores for the fabrication of blue organic light emitting diodes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-10-28 | — | — | US | disclosed |