Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.62 |
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
| ▸ | HPGD | P15428 | 9/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14019143 | 0.96 | NPC1 (0.68) | NPC1RAB9AHPGDKDM4EALDH1A1 | |
| SCHEMBL14981161 | 0.87 | MAPT (0.59) | HPGDKDM4EALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL14019097 | 0.82 | MAPT (0.57) | HPGDKDM4EALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL14019113 | 0.81 | NPC1 (0.64) | NPC1RAB9AHPGDKDM4EALDH1A1 | |
| SCHEMBL5979409 | 0.81 | MAPT (0.51) | HPGDKDM4EALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL14019139 | 0.78 | MAPT (0.53) | NPC1RAB9AHPGDKDM4EALDH1A1 | |
| SCHEMBL14019096 | 0.77 | MAPT (0.59) | HPGDKDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL14019086 | 0.77 | MAPT (0.64) | RAB9AALDH1A1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL14019098 | 0.76 | MAPT (0.57) | HPGDKDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL13134517 | 0.76 | SMN1; SMN2 (0.59) | NPC1RAB9AHPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442447-B2 | Binaphthol based chromophores for the fabrication of blue organic light emitting diodes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-10-28 | — | — | US | disclosed |
| US-7442447-B2 | Binaphthol based chromophores for the fabrication of blue organic light emitting diodes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-10-28 | — | — | US | disclosed |