SCHEMBL14020338

SCHEMBL14020338

CSc1nc(Cl)nc(Nc2ccc3c(O)c(N=Nc4ccc(SC#COOS(=O)(=O)O)cc4S(=O)(=O)O)c(SOOO)cc3c2)n1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CARM1 Q86X55 1/20 0.38
▸ PRMT1 Q99873 1/20 0.38
▸ FUT8 Q9BYC5 1/20 0.35
▸ CD40 P25942 1/20 0.35
▸ CD40LG P29965 1/20 0.35
▸ PTPN11 Q06124 1/20 0.31
▸ ENPP2 Q13822 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14084607 0.96 CARM1 (0.37) CARM1PRMT1FUT8CD40CD40LG
SCHEMBL14020351 0.94 CARM1 (0.38) CARM1PRMT1FUT8ENPP2
SCHEMBL14084623 0.89 CARM1 (0.37) CARM1PRMT1FUT8
SCHEMBL14084614 0.84 PRMT1 (0.41) CARM1PRMT1CD40CD40LGENPP2
SCHEMBL14020352 0.83 FUT8 (0.41) FUT8
SCHEMBL14020342 0.83 PRMT1 (0.40) CARM1PRMT1ENPP2
SCHEMBL14020359 0.82 FUT8 (0.42) FUT8
SCHEMBL14084622 0.81 FUT8 (0.44) FUT8
SCHEMBL14020350 0.80 FUT8 (0.43) FUT8
SCHEMBL14020355 0.80 FUT8 (0.32) CARM1PRMT1FUT8PTPN11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7439340-B2 For exhaust dyeing, cold batch-up dyeing and continuous dyeing EVERLIGHT USA, INC. (US) 2008-10-21 — — US disclosed
US-20080039614-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group EVERLIGHT USA, INC. (US) 2008-02-14 — — US disclosed
Send feedback