SCHEMBL14020355

SCHEMBL14020355

CSc1nc(Cl)nc(Nc2ccc(S(=O)(=O)O)c3cc(SOOO)c(N=Nc4ccc(SC#COOS(=O)(=O)O)cc4)c(O)c23)n1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ FUT8 Q9BYC5 1/20 0.32
▸ PTPN11 Q06124 1/20 0.32
▸ CARM1 Q86X55 1/20 0.31
▸ PRMT1 Q99873 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14084621 0.95 FUT8 (0.32) FUT8PTPN11CARM1PRMT1
SCHEMBL13420796 0.82 FUT8 (0.43) FUT8PTPN11CARM1PRMT1
SCHEMBL14020352 0.81 FUT8 (0.41) FUT8
SCHEMBL14020359 0.81 FUT8 (0.42) FUT8
SCHEMBL14020338 0.80 CARM1 (0.38) FUT8PTPN11CARM1PRMT1
SCHEMBL14084614 0.78 PRMT1 (0.41) CARM1PRMT1
SCHEMBL14020351 0.77 CARM1 (0.38) FUT8CARM1PRMT1
SCHEMBL14084622 0.76 FUT8 (0.44) FUT8
SCHEMBL14084616 0.76 FUT8 (0.42) FUT8
SCHEMBL14020342 0.76 PRMT1 (0.40) CARM1PRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7439340-B2 For exhaust dyeing, cold batch-up dyeing and continuous dyeing EVERLIGHT USA, INC. (US) 2008-10-21 — — US disclosed
US-20080039614-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group EVERLIGHT USA, INC. (US) 2008-02-14 — — US disclosed
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