Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 13/20 | 0.60 |
| ▸ | KIT | P10721 | 7/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13765907 | 0.95 | ABL1 (0.61) | ABL1KIT | |
| SCHEMBL4097590 | 0.86 | ABL1 (0.74) | ABL1KIT | |
| SCHEMBL22529501 | 0.83 | ABL1 (0.69) | ABL1KIT | |
| SCHEMBL22549183 | 0.82 | ABL1 (0.68) | ABL1KIT | |
| SCHEMBL13771968 | 0.81 | ABL1 (0.55) | ABL1KIT | |
| SCHEMBL24626017 | 0.80 | KIT (0.82) | ABL1KIT | |
| SCHEMBL29675112 | 0.80 | KIT (0.82) | ABL1KIT | |
| SCHEMBL16769346 | 0.80 | KIT (0.63) | ABL1KIT | |
| SCHEMBL15006468 | 0.79 | KIT (0.70) | ABL1KIT | |
| SCHEMBL13765822 | 0.79 | KIT (0.71) | ABL1KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007133560-A9 | ACETYLENIC HETEROARYL COMPOUNDS | ARIAD PHARMA INC (US) | 2008-11-13 | — | — | WO | disclosed |
| WO-2007133560-A2 | ACETYLENIC HETEROARYL COMPOUNDS | ARIAD PHARMACEUTICALS, INC. (US) | 2007-11-22 | — | — | WO | disclosed |