Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 1/20 | 0.42 |
| ▸ | EIF4E | P06730 | 6/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.36 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30132996 | 0.96 | RIPK2 (0.42) | RIPK2EIF4EPSEN1PSEN2APH1B | |
| SCHEMBL3902497 | 0.96 | RIPK2 (0.42) | RIPK2EIF4EPSEN1PSEN2APH1B | |
| SCHEMBL31265245 | 0.93 | RIPK2 (0.38) | RIPK2EIF4EPSEN1PSEN2APH1B | |
| SCHEMBL30132994 | 0.88 | CSNK1E (0.38) | CHRM3CSNK1EAKR1C3AKR1C2GRM5 | |
| SCHEMBL19436813 | 0.88 | CSNK1E (0.38) | CHRM3CSNK1EAKR1C3AKR1C2GRM5 | |
| SCHEMBL16972201 | 0.87 | GRM2 (0.42) | CSNK1EGRM2 | |
| SCHEMBL30132999 | 0.86 | RIPK2 (0.44) | RIPK2EIF4EPSEN1PSEN2APH1B | |
| SCHEMBL3788878 | 0.85 | CHRM3 (0.36) | RIPK2EIF4EPSEN1PSEN2APH1B | |
| SCHEMBL30132990 | 0.84 | RIPK2 (0.44) | RIPK2EIF4ECHRM3AKR1C3AKR1C2 | |
| SCHEMBL30132981 | 0.83 | CSNK1E (0.38) | CHRM3CSNK1EAKR1C3AKR1C2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3490981-A1 | SUBSTITUTED HALOGEN(THIO)ACYL COMPOUNDS | Bayer CropScience Aktiengesellschaft (DE) | 2019-06-05 | — | — | EP | disclosed |
| WO-2018019711-A1 | SUBSTITUTED HALOGEN(THIO)ACYL COMPOUNDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-02-01 | — | — | WO | disclosed |
| EP-2465851-A1 | 1-Aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof | Aventis Agriculture (FR) | 2012-06-20 | — | — | EP | disclosed |
| EP-2257530-B1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLANILIDES | BAYER CROPSCIENCE AG (DE) | 2011-10-12 | — | — | EP | disclosed |
| EP-2292098-A1 | Combinations comprising a fungicidal strain and at least one additional fungicide | BASF SE (DE) | 2011-03-09 | — | — | EP | disclosed |
| EP-2109366-A2 | PESTICIDAL MIXTURES | BASF SE (DE) | 2009-10-21 | — | — | EP | disclosed |
| EP-2091326-A2 | PESTICIDAL COMPOSITION COMPRISING A SYNTHETIC COMPOUND USEFUL AS NODULATION AGENT OF LEGUMINOUS PLANTS AND A FUNGICIDE COMPOUND | Bayer CropScience SA (FR) | 2009-08-26 | — | — | EP | disclosed |
| EP-2091327-A2 | PESTICIDAL COMPOSITION COMPRISING A SYNTHETIC COMPOUND USEFUL AS NODULATION AGENT OF LEGUMINOUS PLANTS AND AN INSECTICIDE COMPOUND | Bayer CropScience SA (FR) | 2009-08-26 | — | — | EP | disclosed |
| WO-2008095913-A2 | PESTICIDAL MIXTURES | BASF SE (DE) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008071674-A2 | PESTICIDAL COMPOSITION COMPRISING A SYNTHETIC COMPOUND USEFUL AS NODULATION AGENT OF LEGUMINOUS PLANTS AND AN INSECTICIDE COMPOUND | BAYER CROPSCIENCE SA (FR) | 2008-06-19 | — | — | WO | disclosed |
| WO-2008071672-A2 | PESTICIDAL COMPOSITION COMPRISING A SYNTHETIC COMPOUND USEFUL AS NODULATION AGENT OF LEGUMINOUS PLANTS AND A FUNGICIDE COMPOUND | BAYER CROPSCIENCE SA (FR) | 2008-06-19 | — | — | WO | disclosed |