SCHEMBL16972201

SCHEMBL16972201

Cn1nc(C(F)F)c(C(N)=O)c1-c1ccc(F)cc1-c1ccc(F)cc1Cl

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 3/20 0.42
SCN10A Q9Y5Y9 1/20 0.39
HTR5A P47898 1/20 0.36
PTPN11 Q06124 1/20 0.35
HSD11B1 P28845 1/20 0.35
CSNK1D P48730 3/20 0.35
CSNK1E P49674 3/20 0.35
P2RX7 Q99572 3/20 0.34
CNR1 P21554 2/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
DPP4 P27487 2/20 0.33
BTK Q06187 1/20 0.33
DPP7 Q9UHL4 1/20 0.33
CDC7 O00311 1/20 0.32
DBF4 Q9UBU7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3865441 0.89 CSNK1D (0.38) GRM2PTPN11HSD11B1CSNK1DCSNK1E
SCHEMBL1402165 0.87 RIPK2 (0.42) GRM2CSNK1E
SCHEMBL28483197 0.86 DHODH (0.36) GRM2CSNK1DCSNK1E
SCHEMBL25437339 0.86 GRM2 (0.41) GRM2SCN10AHTR5APTPN11HSD11B1
SCHEMBL3902497 0.85 RIPK2 (0.42) GRM2CSNK1E
SCHEMBL30132996 0.85 RIPK2 (0.42) GRM2CSNK1E
SCHEMBL1762650 0.83 ALDH1A1 (0.39) GRM2HSD11B1CNR1NPC1RAB9A
SCHEMBL30132994 0.83 CSNK1E (0.38) CSNK1DCSNK1EDPP4DPP7
SCHEMBL19436813 0.83 CSNK1E (0.38) CSNK1DCSNK1EDPP4DPP7
SCHEMBL1763226 0.82 CSNK1E (0.41) CSNK1DCSNK1E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116456831-A Biological insecticide 坎纳尔地球科学有限公司 2023-07-18 CN disclosed
CN-115633698-A Compositions and methods for improving plant growth FMC有限公司 2023-01-24 CN disclosed
WO-2015116638-A1 METHODS FOR CONTROLLING WEEDS USING FORMULATIONS CONTAINING FLUTHIACET-METHYL AND HPPD HERBICIDES FMC CORPORATION (US) 2015-08-06 WO disclosed