⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8508228 | 0.80 | — | — | |
| SCHEMBL8447334 | 0.80 | — | — | |
| SCHEMBL19553620 | 0.72 | — | — | |
| SCHEMBL14743779 | 0.70 | — | — | |
| SCHEMBL1600618 | 0.61 | — | — | |
| SCHEMBL6033819 | 0.59 | — | — | |
| SCHEMBL29394145 | 0.57 | — | — | |
| SCHEMBL4146881 | 0.57 | — | — | |
| SCHEMBL73936 | 0.55 | — | — | |
| SCHEMBL7048242 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2475674-B1 | PROBES COMPRISING FLUORESCENT ARTIFICIAL NUCLEOBASES AND USE THEREOF FOR DETECTION OF SINGLE BASE ALTERATION | HUMBOLDT UNIVERSITÄT ZU BERLIN (DE) | 2017-01-25 | — | — | EP | claimed |
| EP-3040341-A1 | PROBES COMPRISING FLUORESCENT ARTIFICIAL NUCLEOBASES AND USE THEREOF FOR DETECTION OF SINGLE BASE ALTERATION | Humboldt-Universität zu Berlin (DE) | 2016-07-06 | — | — | EP | claimed |
| EP-2475674-B1 | PROBES COMPRISING FLUORESCENT ARTIFICIAL NUCLEOBASES AND USE THEREOF FOR DETECTION OF SINGLE BASE ALTERATION | HUMBOLDT UNIVERSITÄT ZU BERLIN (DE) | 2017-01-25 | — | — | EP | disclosed |
| EP-3040341-A1 | PROBES COMPRISING FLUORESCENT ARTIFICIAL NUCLEOBASES AND USE THEREOF FOR DETECTION OF SINGLE BASE ALTERATION | Humboldt-Universität zu Berlin (DE) | 2016-07-06 | — | — | EP | disclosed |
| US-9206218-B2 | Probes comprising fluorescent artificial nucleobases and use thereof for detection of single base alteration | HUMBOLDT-UNIVERSITAT ZU BERLIN (DE) | 2015-12-08 | — | — | US | disclosed |
| US-20120208178-A1 | PROBES COMPRISING FLUORESCENT ARTIFICIAL NUCLEOBASES AND USE THEREOF FOR DETECTION OF SINGLE BASE ALTERATION | HUMBOLDT-UNIVERSITAT ZU BERLIN (DE) | 2012-08-16 | — | — | US | disclosed |
| EP-2475674-A2 | PROBES COMPRISING FLUORESCENT ARTIFICIAL NUCLEOBASES AND USE THEREOF FOR DETECTION OF SINGLE BASE ALTERATION | Humboldt Universität zu Berlin (DE) | 2012-07-18 | — | — | EP | disclosed |
| WO-2011029835-A2 | PROBES COMPRISING FLUORESCENT ARTIFICIAL NUCLEOBASES AND USE THEREOF FOR DETECTION OF SINGLE BASE ALTERATION | HUMBOLDT-UNIVERSITÄT ZU BERLIN (DE) | 2011-03-17 | — | — | WO | disclosed |
| EP-2292633-A1 | Probes comprising fluorescent artificial nucleobases and use thereof for detection of single base alteration | Humboldt Universität zu Berlin (DE) | 2011-03-09 | — | — | EP | disclosed |