Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1194306 | 0.89 | P2RX7 (0.78) | P2RX7 | |
| SCHEMBL1195425 | 0.88 | P2RX7 (0.72) | P2RX7 | |
| SCHEMBL1195746 | 0.87 | P2RX7 (0.71) | P2RX7 | |
| SCHEMBL1194901 | 0.84 | P2RX7 (0.66) | P2RX7 | |
| SCHEMBL12810353 | 0.83 | P2RX7 (0.74) | P2RX7 | |
| SCHEMBL1195703 | 0.83 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL1195740 | 0.83 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL1195510 | 0.83 | P2RX7 (0.77) | P2RX7 | |
| SCHEMBL1194273 | 0.82 | P2RX7 (0.73) | P2RX7 | |
| SCHEMBL1194877 | 0.82 | P2RX7 (1.00) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008138876-A1 | PYRAZOLE DERIVATIVES AS P2X7 MODULATORS | GLAXO GROUP LIMITED (GB) | 2008-11-20 | — | — | WO | disclosed |