Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 3/20 | 0.50 |
| ▸ | CNR2 | P34972 | 3/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1402311 | 1.00 | CHRNB2 (0.55) | CHRNB2CHRNA4CNR1CNR2MTNR1A | |
| SCHEMBL11574802 | 0.93 | CHRNB2 (0.58) | CHRNB2CHRNA4CNR1CNR2MTNR1A | |
| 1-Hydroxy-3-Isopentoxybenzene SCHEMBL2850085 | 0.88 | CHRNB2 (0.60) | CHRNB2CHRNA4DRD2DRD4ADRA1D | |
| SCHEMBL17138218 | 0.86 | RARB (0.49) | RARBPRSS1TSHRMAPK1L3MBTL1 | |
| SCHEMBL11243720 | 0.86 | CHRNB2 (0.65) | CHRNB2CHRNA4CNR1CNR2MTNR1A | |
| SCHEMBL16902832 | 0.86 | CHRNB2 (0.65) | CHRNB2CHRNA4CNR1CNR2MTNR1A | |
| SCHEMBL16902831 | 0.86 | CHRNB2 (0.65) | CHRNB2CHRNA4CNR1CNR2MTNR1A | |
| SCHEMBL16902829 | 0.86 | CHRNB2 (0.65) | CHRNB2CHRNA4CNR1CNR2MTNR1A | |
| SCHEMBL9009814 | 0.86 | CHRNB2 (0.65) | CHRNB2CHRNA4CNR1CNR2MTNR1A | |
| SCHEMBL9126822 | 0.86 | CHRNB2 (0.65) | CHRNB2CHRNA4CNR1CNR2MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292208-B1 | EXTERNAL PREPARATION FOR SKIN | SHISEIDO CO LTD (JP) | 2017-07-19 | — | — | EP | disclosed |
| EP-2292208-A1 | EXTERNAL PREPARATION FOR SKIN | Shiseido Company, Ltd. (JP) | 2011-03-09 | — | — | EP | disclosed |